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RADAR review articles
Asenapine has a similar spectrum of benefits and harms to that of other antipsychotics. Asenapine wafers must be taken sublingually twice daily, with no food or drink for 10 minutes afterwards, and are ineffective if swallowed.
The tablets provide equivalent analgesia to that of oxycodone controlled release tablets. The addition of naloxone reduces, but does not eliminate, opioid-induced constipation.
Indacaterol is a new long-acting beta2-agonist PBS listed for maintenance treatment of chronic obstructive pulmonary disease(COPD). It is not indicated for people with acutely deteriorating COPD and should not be used in people with asthma.
The combination of ticagrelor and aspirin reduces the incidence of vascular deaths and myocardial infarctions more than clopidogrel and aspirin. Weigh this against an increased risk of adverse events. Clopidogrel and aspirin may be a better option for people at high risk of bleeding or at increased risk of dyspnoea or bradycardia.
In Brief
Date published: 2011-12-01 00:00:00
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