Accurate, balanced evidence-based information about medicines
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SmallerNPS RADAR: independent, evidence-based assessment of new drugs, new PBS listings and the latest research for doctors, pharmacists and other health professionals. NPS RADAR: independent, evidence-based assessment of new drugs, new PBS listings and the latest research for doctors, pharmacists and other health professionals.
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RADAR review articles
Nebivolol (Nebilet) for chronic heart failure
Nebivolol is a new selective beta1-receptor antagonist for treating chronic heart failure. Nebivolol is an alternative to bisoprolol, carvedilol, and controlled-release metoprolol but has less robust evidence of survival benefit.
Methylnaltrexone injection (Relistor) for opioid-induced constipation in palliative care
Methylnaltrexone is an option for treating opioid-induced constipation in people receiving palliative care who have not responded to adequately titrated laxatives. About half of these people will have a bowel movement within 4 hours of a single dose.
In Brief
The information contained in this material is derived from a critical analysis of a wide range of authoritative evidence. Any treatment decisions based on this information should be made in the context of the clinical circumstances of each patient.
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