NPS RADAR December 2009 NPS RADAR December 2009

NPS RADAR articles provide timely, independent, evidence-based assessment of new drugs, new PBS listings and research for health professionals.

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NPS RADAR December 2009 NPS RADAR>Full Issue>Health Professional Publication NPS RADAR articles provide timely, independent, evidence-based assessment of new drugs, new PBS listings and research for health professionals.
Olanzapine depot injection (Zyprexa Relprevv) for schizophrenia NPS RADAR>Review>Health Professional Publication Olanzapine pamoate is a long-acting injectable form of olanzapine. Post-injection syndrome can occur: monitor for signs and symptoms for at least 3 hours after administration.
Prasugrel (Effient) for acute coronary syndrome in people undergoing percutaneous coronary intervention NPS RADAR>Review>Health Professional Publication Prasugrel is an alternative to clopidogrel for acute coronary syndrome managed by percutaneous coronary intervention in combination with aspirin. It reduces the risk of atherothrombotic events more than clopidogrel, but at the expense of more bleeding.
Immediate-release pramipexole (Sifrol) and extended-release pramipexole (Sifrol ER) for Parkinson’s disease NPS RADAR>Review>Health Professional Publication Pramipexole is a non-ergot dopamine agonist for treating early Parkinson’s disease. Sleep attacks and compulsive behaviour have been reported with pramipexole and other dopamine agonists
Montelukast (Singulair) PBS listed for exercise-induced asthma in children aged 6–14 years NPS RADAR>Brief Item>Health Professional Publication The PBS listing for montelukast 5 mg tablets was extended on 1 December 2009 to include preventing exercise-induced asthma in children aged 6–14 years.
New pneumococcal polysaccharide conjugate vaccine (Synflorix) added to the national immunisation schedule NPS RADAR>Brief Item>Health Professional Publication The PBAC has recommended listing the 10-valent pneumococcal polysaccharide conjugate vaccine, Synflorix, on the National Immunisation Program.
Etoricoxib (Arcoxia): be aware of hypertension risk NPS RADAR>Brief Item>Health Professional Publication The PBAC has rejected an application to list etoricoxib on the PBS for osteoarthritis, concluding that there was no demonstrated need to list another COX-2 selective NSAID and that etoricoxib appears to cause more episodes of hypertension than celecoxib.
Varenicline (Champix) safety update: serious neuropsychiatric and dermatological adverse events NPS RADAR>Brief Item>Health Professional Publication Serious neuropsychiatric symptoms and severe skin reactions have been reported in people taking varenicline. Updated advice on managing neuropsychiatric symptoms and a precaution about rare but potentially fatal skin reactions have been added to the product information.
Child–Pugh classification of liver disease NPS RADAR>Web Only Item>Health Professional Publication Provides classification used to assess the prognosis of chronic liver disease (mainly cirrhosis) as additional content to prasugrel use for acute coronary syndrome.

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Date published: 2009-12-01 00:00:00

The information contained in this material is derived from a critical analysis of a wide range of authoritative evidence. Any treatment decisions based on this information should be made in the context of clinical circumstances of each patient.

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