NPS RADAR April 2009 NPS RADAR April 2009

NPS RADAR articles provide timely, independent, evidence-based assessment of new drugs, new PBS listings and research for health professionals.

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NPS RADAR April 2009 NPS RADAR>Full Issue>Health Professional Publication NPS RADAR articles provide timely, independent, evidence-based assessment of new drugs, new PBS listings and research for health professionals.
Zoledronic acid (Aclasta) for osteoporosis NPS RADAR>Review>Health Professional Publication The PBS listing of zoledronic acid has been extended and now covers osteoporosis in any postmenopausal woman aged 70 years or older who has a bone mineral density (BMD) T-score less than or equal to –3.0. The NPS RADAR review has been updated accordingly.
Pramipexole (Sifrol) for severe primary restless legs syndrome NPS RADAR>Review>Health Professional Publication Pramipexole may be useful for people with diagnosed restless legs syndrome who have daily symptoms, when non-drug measures prove ineffective. It can cause sudden-onset daytime sleep, and rare cases of compulsive behaviour have been reported.
Ziprasidone (Zeldox): another atypical antipsychotic listed for acute mania in bipolar disorder NPS RADAR>Brief Item>Health Professional Publication Ziprasidone’s efficacy in acute mania comes from 2 short trials. Be aware of dosing, which is twice daily with food. Although weight gain is less likely than with other atypical antipsychotics, there are few data about long-term risks, including diabetes.
Sublingual desmopressin PBS listed — where does desmopressin fit in primary nocturnal enuresis? NPS RADAR>Brief Item>Health Professional Publication Enuresis alarms remain the first choice for primary nocturnal enuresis. Desmopressin sublingual wafers may be easier to take than desmopressin tablets, and might be considered when an alarm is ineffective or contraindicated.
Clopidogrel (Iscover, Plavix) PBS listing extended to cardiac stent insertion NPS RADAR>Brief Item>Health Professional Publication Clopidogrel, in combination with aspirin, can be prescribed on the PBS following coronary artery stent insertion.

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Date published: 2009-04-01 00:00:00

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