NPS RADAR August 2007 NPS RADAR August 2007

NPS RADAR articles provide timely, independent, evidence-based assessment of new drugs, new PBS listings and research for health professionals.

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NPS RADAR August 2007 NPS RADAR>Full Issue>Health Professional Publication NPS RADAR articles provide timely, independent, evidence-based assessment of new drugs, new PBS listings and research for health professionals.
Risedronate sodium (Actonel) and risedronate sodium with calcium carbonate (Actonel Combi) listing for osteoporosis in patients at high risk of fracture NPS RADAR>Brief Item>Health Professional Publication The PBS restriction for risedronate was extended o allow the treatment of osteoporosis among patients aged 70 years or older with low bone mineral density scores but without an existing minimal trauma fracture.
Levonorgestrel-releasing intrauterine device (Mirena) now PBS listed for idiopathic menorrhagia NPS RADAR>Brief Item>Health Professional Publication The restricted PBS listing for levonorgestrel-releasing intrauterine device (Mirena) was extended to include women in whom oral therapies for idiopathic menorrhagia are ineffective or contraindicated.
Be aware of dose ranges for new ramipril with felodipine combination (Triasyn) (see erratum below) NPS RADAR>Brief Item>Health Professional Publication A new fixed-dose combination preparation of ramipril with felodipine (Triasyn) was PBS listed with a restricted dose range and dose titration cautions.
Perindopril arginine with indapamide hemihydrate (Coversyl Plus) NPS RADAR>Brief Item>Health Professional Publication Perindopril arginine with indapamide (Coversyl Plus) was PBS listed after a formulation change from perindopril erbumine to perindopril arginine.
Alternative hydroxocobalamin product PBS listed NPS RADAR>Brief Item>Health Professional Publication Hydroxocobalamin (Goldshield Hydroxocobalamin) has been temporarily PBS listed to provide an alternative to the currently listed product (Neo-Cytamen) while it is in short supply.
Cholinesterase inhibitors: change in authority requirements for cognitive testing NPS RADAR>Brief Item>Health Professional Publication A change in the authority requirements for the cholinesterase inhibitors (donepezil hydrochloride, galantamine hydrochloride and rivastigmine hydrogen tartrate) means that the same cognitive test used in the initial treatment authority application must be used in requests for continued treatment.
Benzhexol hydrochloride misuse NPS RADAR>Brief Item>Health Professional Publication Prescribers are reminded that benzhexol hydrochloride, an anticholinergic used in the treatment of Parkinson's disease and drug-induced extrapyramidal disorders, is a potential drug of abuse and that overdoses can be fatal.
Rosiglitazone and cardiovascular risk - NPS fact sheet NPS RADAR>Brief Item>Health Professional Publication NPS has released a fact sheet discussing a recent meta-analysis that has raised concerns about a potential increase in cardiovascular risk among patients treated with rosiglitazone.
Additional content: Olmesartan medoxomil monotherapy or in combination with hydrochlorothiazide for hypertension NPS RADAR>Web Only Item>Health Professional Publication Table of questions to ask about fixed-dose combination preparations of olmesartan and hydrochlorothiazide for hypertension.
Budesonide with eformoterol dry powder inhaler (Symbicort) maintenance and reliever regimen for asthma NPS RADAR>Review>Health Professional Publication Reviews extended PBS listing for budesonide/eformoterol combination inhaler as an on-demand alternative to regular combination or corticosteroid therapy for asthma.
Fluticasone propionate with salmeterol xinafoate (Seretide) for chronic obstructive pulmonary disease NPS RADAR>Review>Health Professional Publication The PBS listing of fluticasone with salmeterol has been extended to include patients with moderate to severe COPD with symptoms that are poorly controlled despite regular beta2 agonist treatment.
Olmesartan medoxomil (Olmetec) monotherapy or in combination with hydrochlorothiazide (Olmetec Plus) for hypertension NPS RADAR>Review>Health Professional Publication Reviews use of olmesartan monotherapy or in combination with hydrochlorothiazide for hypertension, including indications for use, drug interactions, and patient monitoring

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Date published: 2007-08-01 00:00:00

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