NPS RADAR March 2009 NPS RADAR March 2009

NPS RADAR articles provide timely, independent, evidence-based assessment of new drugs, new PBS listings and research for health professionals.

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Title Why read this
Risedronate (Actonel and Actonel Once-a-Week) for corticosteroid-induced osteoporosis NPS RADAR>Brief Item>Health Professional Publication The PBS listing for risedronate (Actonel and Actonel Once-a-Week) and risedronate with calcium (Actonel Combi) has been extended to people with corticosteroid-induced osteoporosis (CIO) who are on long-term high-dose corticosteroid therapy.
Desvenlafaxine (Pristiq) for major depressive disorder NPS RADAR>Review>Health Professional Publication Theoretically, desvenlafaxine has lower potential for drug interactions than its parent drug venlafaxine, but this does not appear to confer any particular clinical advantage.
Valsartan (Diovan) and combinations with hydrochlorothiazide (Co-Diovan) or amlodipine (Exforge) NPS RADAR>Review>Health Professional Publication Valsartan reduces blood pressure to a similar extent as other angiotensin II-receptor antagonists. If blood pressure is not controlled by valsartan 160 mg, add a second drug rather than increasing the dose to 320 mg. Establish the effective dose using the individual drugs before prescribing the appropriate combination.
Clopidogrel (Iscover, Plavix) PBS listing extended to include acute coronary syndrome (ACS) in combination with aspirin NPS RADAR>Brief Item>Health Professional Publication Clopidogrel (Iscover, Plavix) and aspirin can now be prescribed in combination for acute coronary syndrome (ACS). The extended listing includes the treatment of myocardial infarction (MI) or unstable angina to prevent atherothrombotic events.

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Date published: 2009-03-01 00:00:00

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