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Articles on Avandamet (rosiglitazone with metformin) from NPS RADARArticles on Avandamet (rosiglitazone with metformin) from NPS RADAR
| Title | Content Type | Date | Description |
|---|---|---|---|
| Rosiglitazone (Avandia) and rosiglitazone with metformin (Avandamet) for type 2 diabetes mellitus | Professional publication - NPS RADAR - Review | 2008-12-01 00:00:00 | Rosiglitazone improves glycaemic control but there is a lack of evidence that it improves diabetes–related clinical complications and mortality. Rosiglitazone is no longer indicated in combination with insulin or for triple oral therapy in combination with metformin and a sulfonylurea. Rosiglitazone is a third-line choice. It may still be considered as part of dual therapy when either metformin or a sulfonylurea is contraindicated or not tolerated. Insulin should also be considered instead of rosiglitazone in these scenarios. Do not use rosiglitazone in people with heart failure or a history of heart failure. |
| Rosiglitazone with metformin combination tablets (Avandamet) listed on the PBS. | Professional publication - NPS RADAR - Brief item | 2006-12-01 00:00:00 | Rosiglitazone with metformin in a fixed-dose combination tablet (Avandamet) was listed on the PBS as a third-line choice, after metformin and/or a sulfonylurea. |
View all RADAR articles by date, by therapeutic topic, or by active ingredient, or find out more about NPS RADAR.
NPS RADAR: independent, evidence-based assessment of new drugs, new PBS listings and the latest research for doctors, pharmacists and other health professionals.
Date published: 2009-10-30 00:00:00
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References to brands should not be taken as an endorsement by NPS.
