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| Title | Content Type | Date | Description |
|---|---|---|---|
| Rosiglitazone (Avandia) and rosiglitazone with metformin (Avandamet) for type 2 diabetes mellitus | Professional publication - NPS RADAR - Review | 2008-12-01 00:00:00 | Rosiglitazone improves glycaemic control but there is a lack of evidence that it improves diabetes–related clinical complications and mortality. Rosiglitazone is no longer indicated in combination with insulin or for triple oral therapy in combination with metformin and a sulfonylurea. Rosiglitazone is a third-line choice. It may still be considered as part of dual therapy when either metformin or a sulfonylurea is contraindicated or not tolerated. Insulin should also be considered instead of rosiglitazone in these scenarios. Do not use rosiglitazone in people with heart failure or a history of heart failure. |
| Rosiglitazone and cardiovascular risk - NPS fact sheet | Professional publication - NPS RADAR - Brief item | 2007-08-01 00:00:00 | NPS has released a fact sheet discussing a recent meta-analysis that has raised concerns about a potential increase in cardiovascular risk among patients treated with rosiglitazone. |
| Pioglitazone (Actos) and rosiglitazone (Avandia) authority wording changed | Professional publication - NPS RADAR - Brief item | 2006-08-01 00:00:00 | The wording of the PBS requirements for pioglitazone (Actos) and rosiglitazone (Avandia) changed on 1 August 2006. The changes are intended to simplify the listings, and there are no changes to the authority requirements. |

NPS RADAR: independent, evidence-based assessment of new drugs, new PBS listings and the latest research for doctors, pharmacists and other health professionals.
Date published: 2009-10-30 00:00:00
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References to brands should not be taken as an endorsement by NPS.