Citalopram interactions

Do not take citalopram with

  • any of the other medicines listed in the table Medicines that may increase risk of serotonin toxicity, unless under careful medical supervision
  • illegal drugs
  • moclobemide and wait at least 2 days after stopping moclobemide before taking citalopram, because it may cause serotonin toxicity or a serious reaction with severe high blood pressure.

See also

Tell your doctor if you are taking any of the following

Always tell your doctor about all other medicines you are taking, including over-the-counter and complementary or alternative medicines. You may need careful monitoring or a change in dose to avoid side effects if you are taking other medicines, including:

  • ketoconazole (Nizoral) and itraconazole (Sporanox), medicines used to treat fungal infections
  • antibiotics such as erythromycin (EES, E-Mycin, Eryc) and clarithromycin (Clarac, Clarihexal, Clarithro, Kalixocin, Klacid, Nexium Hp7 combination pack, Probitor Hp7 Combination pack)
  • medicines used to treat gastric reflux and stomach ulcers, such as cimetidine (Magicul, Tagamet) and omeprazole (Acimax, Losec, Meprazol, Omepral, Ozmep, Pemzo, Probitor)
  • medicines that can thin the blood, such as aspirin and other NSAIDs
  • medicines that increase the risk of gastrointestinal bleeding such as warfarin (Coumadin, Marevan), ticlopidine (Tilodene), aspirin (Aspro), and NSAIDs, used to treat pain and inflammation
  • tramadol (Durotram, Lodam, Tramal, Tramedo, Zydol), used to relieve pain
  • carbamazepine (Tegretol, Teril), a medicine used to treat epilepsy
  • some heart medicines, including antiarrhythmics (medicines used to control an irregular heart beat, such as flecainide), and beta-blockers, such as metoprolol (Betaloc, Lopresor, Metohexal, Metrol, Minax, Toprol-XL)
  • selegiline (Eldepryl, Selgene), a medicine used to treat Parkinson’s disease
  • tryptophan, an amino acid
  • antipsychotic medicines used to treat certain mental health conditions such as schizophrenia, eg, olanzapine (eg, Lanzek, Ozin, Zylap, Zypine, Zyprexa) and risperidone (eg, Ozidal, Resdone, Risperdal)
  • bupropion (Prexaton, Zyban) for stopping smoking.

Citalopram and alcohol

Citalopram is not likely to increase the effects of alcohol, but alcohol can make you feel worse if you are depressed.

Who can I ask about interactions?

Call the NPS Medicines Line on 1300 MEDICINE (1300 633 424) to get information about your prescription, over-the-counter and complementary medicines (herbal, ‘natural’, vitamins and minerals) from a pharmacist. Your call will be answered by healthdirect Australia.

Find out more about

If you are starting citalopram, see 10 things you should know about antidepressants.

You can also read more about depression and the options for treating it.

For more information

The consumer medicine information (CMI) for your brand of citalopram is available from our website or a pharmacist. If you have any concerns about interactions, talk to your health professional. The CMI includes:

  • how to take this medicine
  • what to do if you forget to take it
  • if you take too much (overdose)
  • things you must and must not do while taking this medicine
  • signs of severe reactions and what to do.
  • Rossi S, ed. eAMH [online]. Adelaide: Australian Medicines Handbook, 2012. (Accessed 9 February 2012).
  • Psychotropic Expert Group. Therapeutic Guidelines: Psychotropic, Version 6. In: eTG complete [CD-ROM]. Melbourne: Therapeutic Guidelines Limited; 2008.
  • Lundbeck Australia Pty Ltd. Cipramil consumer medicine information. March 2011. (Accessed 22 March 2012).