Duloxetine

Active ingredient: Duloxetine

Note about medicines names

Most medicines have two names: the active ingredient and the brand name. The active ingredient is the chemical in the medicine that makes it work. The brand name is the name given to the medicine by its manufacturer. There may be several brands that contain the same active ingredient. This website uses active ingredient names (eg, amoxycillin), with brand names in brackets and with a capital letter (eg, Amoxil). We also discuss medicines in groups or ‘classes’ when their effects or actions are very similar.

To find out more about active ingredients and brand names read our brand choices information.

What is duloxetine?

Duloxetine belongs to a group of medicines called serotonin and noradrenaline reuptake inhibitors (SNRIs). It is used to treat depression and some other conditions.

Find out more about

If you are starting duloxetine, see 10 things you should know about antidepressants.

You can also read more about depression and the options for treating it.

For more information

The consumer medicine information (CMI) for your brand of duloxetine is available from our website or a pharmacist. The CMI includes:

  • how to take this medicine
  • what to do if you forget to take it
  • if you take too much (overdose)
  • things you must and must not do while taking this medicine
  • signs of severe reactions and what to do.
References
  • Australian Medicines Handbook 2015. Adelaide: Australian Medicines Handbook Pty Ltd; 2015 January. [Online].
  • Psychotropic Expert Group. Therapeutic Guidelines: Psychotropic, Version 6. In: eTG complete [CD-ROM]. Melbourne: Therapeutic Guidelines Limited; 2008.
  • Williams JW Jr, Mulrow CD, Chiquette E, et al. A systematic review of newer pharmacotherapies for depression in adults: evidence report summary. Ann Intern Med 2000;132:743–56. [PubMed]
  • Eli Lilly Australia Pty Limited. Cymbalta consumer medicine information. October 2010. (Accessed 22 March 2012).
  • National Collaborating Centre for Mental Health (UK). Depression: the treatment and management of depression in adults (updated edition). Leicester (UK): British Psychological Society, 2010. [PubMed].
  • Gartlehner G, Hansen RA, Morgan LC, et al. Comparative benefits and harms of second-generation antidepressants for treating major depressive disorder: an updated meta-analysis. Ann Intern Med 2011;155:772–85. www.annals.org/content/155/11/772.full.pdf+html (accessed 7 March 2012).

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