Side effects of imipramine
Side effects of tricyclic antidepressants as a group are listed below. Not everyone experiences these side effects — the way an antidepressant affects you is quite individual, so you might need to try more than one to find the one that suits you best. Some of the side effects will last only a week or two after you first start taking the medicine (eg, insomnia, nausea and dizziness), while others (eg, sexual side effects) tend to persist. If you find any side effects troublesome, talk to your doctor about how to manage them, or about switching to another medicine.
Remember that the risk of side effects with any medicine needs to be weighed against its benefit in treating your condition. Your doctor can help you weigh up the risks and benefits of taking particular medicine. See also Is this medicine right for me?
Frequency of side effects with imipramine
|Common (1% of people or more)||Infrequent (between 0.1% and 1% of people)||Rare (fewer than 0.1% of people)|
|This is not a complete list of imipramine’s side effects. See the consumer medicine information (CMI) for more information.|
Imipramine and driving or operating machinery
Do not drive or operate machinery until you know how this medicine affects you.
Who can I ask about side effects?
If you’re concerned that you or someone in your care is having side effects related to a medicine, seek medical advice.
Call the NPS Medicines Line on 1300 MEDICINE (1300 633 424) to get information about your prescription, over-the-counter and complementary medicines (herbal, ‘natural’, vitamins and minerals) from a pharmacist. Your call will be answered by healthdirect Australia.
To report and discuss possible side effects, call the Adverse Medicines Events (AME) line on 1300 134 237 from anywhere in Australia (Mon–Fri, 9am–5pm).
Find out more about
- What imipramine does and how effective it is
- Who imipramine is for and who should be cautious
- Interactions with imipramine
- Brands of imipramine
If you are starting imipramine, see 10 things you should know about antidepressants.
For more information
- Starting, switching and stopping antidepressants
- Managing side effects of antidepressants
- Psychological therapies
The consumer medicine information (CMI) for your brand of imipramine is available from our website or a pharmacist. If you have any concerns about interactions, talk to your health professional. The CMI includes:
- How to take this medicine
- What to do if you forget to take it
- If you take too much (overdose)
- Things you must and must not do while taking this medicine
- Signs of severe reactions and what to do.
- Australian Medicines Handbook 2015. Adelaide: Australian Medicines Handbook Pty Ltd; 2015 January. [Online].