Tetrabenazine Tablets

Tetrabenazine Tablets is a brand of medicine containing the active ingredient tetrabenazine.

Find out more about active ingredients.

Consumer medicine information (CMI) leaflet

Developed by the pharmaceutical company responsible for this medicine in Australia, according to TGA regulations.

TETRABENAZINE TABLETS

Tetrabenazine


Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about Tetrabenazine Tablets. It does not contain all the available information. Reading this leaflet does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of your taking Tetrabenazine Tablets against the benefits they expect it will have for you.

If you have any concerns about taking Tetrabenazine Tablets, ask your doctor or pharmacist.

Keep this leaflet with the medicine. You may need to read it again.

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What Tetrabenazine Tablets are used for

Tetrabenazine is used for the treatment of diseases, which cause jerky, irregular, uncontrollable movements such as Huntington's chorea, senile chorea and hemiballismus.

Tetrabenazine affects some chemicals in the brain, and by doing so it helps to control jerky and irregular movements.

Your doctor may have prescribed Tetrabenazine Tablets for another use. Ask your doctor if you have any questions about why Tetrabenazine Tablets have been prescribed for you.

Tetrabenazine Tablets are not addictive.

Tetrabenazine Tablets are only available on a doctor's prescription.

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Before you take Tetrabenazine Tablets

When you must not take it

Do not take Tetrabenazine Tablets if:

  • You are allergic to tetrabenazine or other ingredients of Tetrabenazine Tablets listed at the end of this leaflet.
    Tetrabenazine tablets contain lactose. It may cause a problem in a small number of people who are sensitive to it.
  • You are taking medicine containing reserpine.
  • You are taking medicine containing levodopa (which is used to treat Parkinson's disease).
  • You are being treated for Parkinson's disease.
  • You are being treated for depression.
  • You are taking central nervous system stimulants or depressants (including alcohol).

These warnings are extremely important as using more than one medicine at the same time can increase or reduce the effect of the medicines. For example, this medicine can increase the effect of some medicines for lowering high blood pressure or for depression (monoamine oxidase inhibitors). Tetrabenazine should not be administered within two weeks of treatment with monoamine oxidase inhibitors.

  • You are breastfeeding.

Do not take Tetrabenazine Tablets after the expiry date printed on the bottle.

Do not take Tetrabenazine Tablets if the bottle seems to have been opened or the tablets do not look quite right (see Product Description).

If you are not sure whether you should start taking this medicine, talk to your doctor.

Before you start to take it

Tell your doctor if you have or have had any of the following medical conditions:

  • Allergy to any other medicines, foods, preservatives or dyes
  • Depression
  • Suicidal thoughts or behaviour
  • Parkinson's disease
  • Abnormal heart rate or rhythm
  • Kidney disease
  • Liver disease

Tell your doctor if you are pregnant or intend to become pregnant or to breastfeed.

If you have not told your doctor about any of the above, tell him/her before you start taking Tetrabenazine Tablets.

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop.

Some medicines and Tetrabenazine Tablets may interfere with each other. These include:

  • Reserpine and levodopa
  • Medicines used to treat depression, such as monoamine oxidase inhibitors (MAOIs) and CYP2D6 inhibitors, such as fluoxetine, paroxetine, quinidine, duloxetine, terbinafine, amiodarone, or sertraline
  • Medicines that affect the brain and nervous system including medication used to treat psychiatric conditions, strong painkillers and medication used to help sleep
  • Medicines used to treat psychosis, such as haloperidol, chlorpromazine and metoclopramide
  • Medicines used to treat high blood pressure
  • Medicines used to treat low blood pressure, such as beta blockers

Some medicines, when used in combination with Tetrabenazine, may interfere with the rate and rhythm of heart beats. These include medications used to treat psychiatric conditions, antibiotics and medications used to treat problems with heart rhythm conditions.

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How to take Tetrabenazine Tablets

Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet.

If you do not understand the instructions on the bottle, ask your doctor or pharmacist for help.

How much to take

The dose required varies from person to person. The usual starting dose in adults is one tablet twice a day. This may increase to a total of 200 mg (8 tablets) a day.

The doctor will decide the best dose for children and elderly patients.

DO NOT TAKE MORE THAN THE DOSE YOUR DOCTOR HAS RECOMMENDED.

If you feel unwell during your course of treatment, tell your doctor.

How to take it

Swallow the tablet or tablets with water or another non-alcoholic drink

When to take it

Take your medicine at about the same time each day. Taking it at the same time each day will have the best effect. It will also help you remember when to take it.

How long to take it

Continue taking your medicine for as long as your doctor tells you. This medicine helps to control your condition, but does not cure it. It is important to keep taking your medicine even if you feel well.

If you forget to take Tetrabenazine Tablets

If you forget to take a dose of Tetrabenazine Tablets, leave out that dose completely. Take your next dose at the normal time it is due.

Do not take a double dose to make up for the dose that you missed. This may increase your chance of you getting an unwanted side effect.

If you have trouble remembering when to take Tetrabenazine Tablets, ask your pharmacist for some hints.

If you take too many Tetrabenazine Tablets

Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26 in Australia) for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too many Tetrabenazine Tablets. Do this even if there are no signs of discomfort or poisoning. Symptoms of an overdose may include nausea, vomiting, diarrhoea, confusion, hallucinations, sedation, drowsiness, sweating, low blood pressure and abnormally low body temperature

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While you are taking Tetrabenazine Tablets

Things you must do

Make sure that all of your doctors and pharmacists know about your use of Tetrabenazine Tablets. Remind them if any new medicines are about to be started.

If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine. It may affect other medicines used during surgery.

If you become pregnant while taking this medicine, tell your doctor immediately.

Things you must not do

Do not use Tetrabenazine Tablets to treat any complaint other than that directed by your doctor. It may not be safe to use Tetrabenazine Tablets for another complaint.

Tetrabenazine Tablets should only be used by the person for whom it was prescribed. Do not give Tetrabenazine Tablets to anyone else even if they have the same condition as you. It may not be safe for another person to use Tetrabenazine Tablets.

Do not stop taking your medicine or change the dosage without checking with your doctor.

Things to be careful of

Be careful driving or operating machinery until you know how Tetrabenazine Tablets affects you. This medicine may cause drowsiness in some people.

If you feel light-headed, dizzy or faint when getting out of bed or standing up, get up slowly. Standing up slowly, especially when you get up from bed or chairs, will help your body get used to the change in position and blood pressure. If this problem continues or get worse, talk to your doctor.

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Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Tetrabenazine Tablets. Like all medicines, Tetrabenazine Tablets may have some side effects. Sometimes they are serious, most of the time they are not.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor or pharmacist if you notice any of the following:

  • Sleepiness and drowsiness
  • Depression
  • Uncontrollable movements of the hands, arms, legs and head (similar to those in Parkinson's disease)
  • Digestive problems
  • Lowering of blood pressure
  • Feeling nervous or anxious
  • Trouble sleeping

Tell your doctor immediately if you notice any of the following:

  • Difficulty in swallowing
  • Choking attacks
  • Stiffness or tightness in the arms or legs
  • Confusion or having thoughts of irrational ideas not shared by others
  • Suicidal thoughts or behaviour

Other side effects not listed above may also occur in some patients. Tell your doctor if you notice anything else that is making you feel unwell.

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After using Tetrabenazine Tablets

Storage

  • Keep Tetrabenazine Tablets in their bottle until it is time to take your dose. If you take them out of their container, they may not keep well.
  • Keep Tetrabenazine Tablets in a cool dry place where the temperature stays below 30°C.
  • Do not store it or any other medicine in the bathroom or near a sink.
  • Do not leave it on a window sill or in the car on hot or cold days. Heat and dampness can destroy some medicines.
  • Keep Tetrabenazine Tablets where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Disposal

If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.

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Product description

What Tetrabenazine Tablets look like

Tetrabenazine Tablets 25 mg are buff. They are scored and marked with "CL" over "25".

Ingredients

Each Tetrabenazine Tablet contains 25 mg of the active ingredient, tetrabenazine, and 64 mg lactose.

Tetrabenazine Tablets also contain the following inactive ingredients:

  • Starch
  • Talc
  • Magnesium stearate
  • Iron oxide yellow

Tetrabenazine Tablets are available in plastic bottles containing 112 tablets.

Manufacturer/Supplier

Tetrabenazine Tablets are distributed in Australia by:
iNova Pharmaceuticals (Australia) Pty Ltd
ABN: 88 000 222 408
Level 10, 12 Help Street
Chatswood NSW 2067
Tel: 1800 253 272

This leaflet was prepared in October 2013

Australian Registration Number:
AUST R 13695

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CMI provided by MIMS Australia, March 2015  

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