Imrest Tablets is a brand of medicine containing the active ingredient zopiclone.
Find out more about active ingredients.
Consumer medicine information (CMI) leaflet
Developed by the pharmaceutical company responsible for this medicine in Australia, according to TGA regulations.
contains the active ingredient zopiclone
Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Imrest.
It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have benefits and risks. Your doctor has weighed the risks of you taking Imrest against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, talk to your doctor or pharmacist.
Keep this leaflet with your medicine. You may need to read it again.
What Imrest is used for
Imrest is used to treat short-term insomnia (trouble sleeping).
Imrest is thought to work by:
- reducing the time needed to fall asleep
- increasing the duration of sleep
- decreasing the number of times that you wake up during the night.
In general, Imrest should only be taken for short periods only (2 to 4 weeks). Continuous long-term use is not recommended as it may lead to physical or psychological dependence.
Ask your doctor if you have any questions about why Imrest has been prescribed for you. Your doctor may have prescribed Imrest for another reason.
Imrest is available only with a doctor's prescription.
Before you take Imrest
When you must not take it
Do not take Imrest if you are allergic to any other medicines containing zopiclone or any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include skin rash, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, wheezing or shortness of breath.
Do not take Imrest if you have:
- been drinking alcohol or you believe that you may have alcohol in your bloodstream
- myasthenia gravis, a condition in which the muscles become severely weak and tire easily
- severe lung or airway problems
- sleep apnoea, a condition where you temporarily stop breathing whilst asleep
- had a stroke
- severe liver problems.
Do not give Imrest to children or adolescents. Safety in children and adolescents under 18 years of age has not been established.
Do not take Imrest if the expiry date (EXP.) printed on the pack has passed. If you take this medicine after the expiry date, it may not work as well or it may have an entirely unexpected effect.
Do not take Imrest if the packaging shows signs of tampering or the tablets do not look quite right.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Before you start to take it
Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.
Tell your doctor if you are pregnant or plan to become pregnant. Imrest may affect your developing baby if you take it during pregnancy. Like most medicines of this kind, Imrest is not recommended to be used during pregnancy. Your doctor will discuss the risks and benefits of taking Imrest during pregnancy.
Tell your doctor if you are breastfeeding or wish to breastfeed. Imrest passes into breast milk and may affect your baby. Your doctor will discuss the risks and benefits of using it if you are breastfeeding or planning to breastfeed.
Tell your doctor if you have, or have had, any medical conditions, especially the following:
- chronic lung or breathing problems
- sleep apnoea
- thyroid problems
- kidney problems
- severe liver problems
- epilepsy (fits or convulsions)
- mental problems such as depression, psychosis, schizophrenia
- drug or alcohol dependence.
If you have ever been addicted to a substance or have ever suffered from a mental illness, you may be at risk of getting into a regular pattern or habit of taking Imrest.
Your doctor may want to take special care if you have any of the above conditions.
Tell your doctor if you drink alcohol regularly. Alcohol may increase the effects of Imrest.
Tell your doctor if you plan to have surgery.
If you have not told your doctor about any of the above, tell them before you start taking Imrest.
Taking other medicines
You must tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
Some medicines may be affected by Imrest, or may affect how well it works. These include:
- other sleeping tablets, sedatives or tranquillisers
- medicines for depression, anxiety and mental illness
- medicines for epilepsy, including carbamazepine, phenytoin
- muscle relaxants
- certain strong pain relievers, eg: codeine
- certain antibiotics such as erythromycin, clarithromycin, rifampicin
- antifungals such as ketoconazole, itraconazole
- ritonavir, an anti-viral used in the treatment of AIDS infections
- St John's wort, a herbal remedy.
These medicines may be affected by Imrest or may affect how well it works. You may need to take different amounts of your medicine or different medicines.
Your doctor can tell you what to do if you are taking any of these medicines.
If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking Imrest.
How to take Imrest
Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the pack, ask your doctor or pharmacist.
How much to take
Imrest should only be taken when you are about to get a full night's sleep (7 to 8 hours) before you need to be active again.
The usual adult dose is one tablet (7.5 mg) just before you go to bed.
People over 65 years old and people with liver problems may need smaller doses. The recommended dose is half a tablet taken just before you go to bed.
Your doctor may advise you to take a different dose. This depends on your condition and whether or not you are taking any other medicines.
Follow the instructions they give to you. If you take the wrong dose, Imrest may not work as well.
Imrest should not be given to children or adolescents less than 18 years of age.
How to take it
Swallow the tablet with a glass of water. Imrest tablets can be broken in half along the breakline if your doctor has prescribed half a tablet.
When to take it
Imrest should be taken when you go to bed. Only take Imrest if you feel you will need help sleeping.
Imrest can be taken with or without food.
If you take Imrest on an empty stomach it may work more quickly and put you to sleep more quickly.
If you are not sure when to take it, ask your doctor or pharmacist.
How long to take it for
Keep taking Imrest for as long as your doctor tells you to. Usually, Imrest is taken for short periods only (for example 2 to 4 weeks). Continuous long-term use is not recommended unless advised by your doctor. The use of Imrest long-term may lead to dependence on the medicine.
Ask your doctor or pharmacist if you are not sure how long to take the medicine for.
If you forget to take it
If you forget to take Imrest before you go to bed and you wake up late in the night or very early in the morning, do not take Imrest as you may have trouble waking in the morning or experience morning drowsiness.
Take the next dose the following night when you are meant to.
If you are not sure what to do or have any questions, ask your doctor or pharmacist.
If you take too much (overdose)
Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much Imrest. Do this even if there are no signs of discomfort or poisoning. If you take too much Imrest, you may feel drowsy, lack energy and coordination and feel unsteady when walking.
While you are taking Imrest
Things you must do
Before starting any new medicine, tell your doctor or pharmacist that you are taking Imrest.
Tell all the doctors, dentists and pharmacists who are treating you that you are taking Imrest.
Tell your doctor if you think Imrest is not helping you to sleep.
If you become pregnant while taking Imrest, stop taking it and tell your doctor immediately.
If you plan to have surgery (that needs a general anaesthetic), including dental surgery, tell your doctor or dentist that you are taking Imrest.
Things you must not do
Do not take Imrest for a longer time than your doctor has prescribed. Imrest should be taken for short periods only (for example 2 to 4 weeks) unless advised otherwise by your doctor.
Do not stop taking Imrest, or change the dose, without checking with your doctor. Stopping Imrest suddenly may cause some unwanted effects such as anxiety, tremor, sweating, headache, confusion and palpitations. For patients on prolonged treatment, insomnia may recur if Imrest treatment is stopped abruptly. Your doctor will gradually reduce the amount of Imrest you are taking before stopping completely.
Do not drink alcohol before or after taking this medicine. This can increase the risk of side effects.
Do not use Imrest to treat any other conditions unless your doctor tells you to.
Do not give Imrest to anyone else, even if they have the same condition as you.
Things to be careful of
Be careful driving or operating machinery until you know how Imrest affects you.
Because Imrest will make you sleepy, you should not operate dangerous machinery or drive motor vehicles for 8 hours after you take it. Imrest may cause drowsiness or loss of coordination in some people. Even though you take Imrest at night, you may still be affected the next day. Make sure you know how Imrest affects you before you drive a car, operate machinery or do anything else that could be dangerous.
Be careful when drinking alcohol while taking Imrest. Your tolerance for alcohol may be lower than usual when taking Imrest. Combining Imrest and alcohol may cause unwanted side effects. Your doctor may suggest that you avoid alcohol or reduce the amount of alcohol you drink while you are taking Imrest.
Be careful if you are elderly, unwell or taking other medicines.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Imrest. Imrest helps most people with insomnia, but it may have unwanted side effects in some people.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
If you are over 65 years of age, you may have an increased chance of getting side effects.
Do not be alarmed by this list of possible side effects. You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
Common side effects
- bitter taste in mouth, dry mouth
- drowsiness, fatigue
Less common side effects
- heartburn, nausea, vomiting, stomach pains,
- change in appetite
- blurred vision.
Tell your doctor as soon as possible if you notice any of the following:
- agitation, anxiety, depression
- loss of memory
- skin rash or itch
- confusion, dizziness
- blurred vision
- unusual tiredness or weakness
- lack of coordination
- fast or irregular heartbeat (elderly patients).
- sleep walking, or similar inappropriate behaviours such as 'sleep driving', preparing and eating food, or making phone calls whilst half asleep
Alcohol can increase the risk of sleep walking or other behaviours such as driving or eating food whilst asleep. This risk is also increased if you take more than the recommended dose.
Some sleep medicines may cause a short-term memory loss. When this occurs, a person may not remember what has happened for several hours after taking the medicine. This is not usually a problem since most people fall asleep after taking the medicine.
Sleep medicines should in most cases, be used only for short periods of time. If your sleep problems continue, consult your doctor.
Some medicines can cause dependence, especially when they are used regularly for longer than a few weeks. People who have been dependent on alcohol or other drugs in the past may have a higher chance of becoming addicted to sleep medicines. If you have been addicted to alcohol or drugs in the past, it is important to tell your doctor before starting Imrest.
If any of the following happen, stop taking this medicine and tell your doctor immediately, or go to Accident and Emergency at your nearest hospital:
- swelling of the face, lips, mouth or throat, which may cause difficulty in swallowing or breathing
The above list includes serious side effects which may require medical attention. These side effects are very rare.
Tell your doctor if you notice anything that is making you feel unwell. Other side effects not listed above may also occur in some patients.
After taking Imrest
Sometimes when medicines are stopped suddenly, after being used for a long time, withdrawal symptoms may occur. Symptoms of withdrawal may include abdominal and muscle cramps, vomiting and sweating.
In some cases your insomnia may appear worse for a short time; speak to your doctor if this occurs.
Tell your doctor if you have any problems when you stop taking Imrest.
If you have any query about any aspect of your medicine, or any questions regarding the information in this leaflet, discuss them with your doctor or pharmacist.
Keep Imrest where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the pack they will not keep well.
Keep your tablets in a cool dry place where the temperature stays below 25°C.
Do not store Imrest or any other medicine in the bathroom or near a sink.
Do not leave Imrest in the car or on window sills. Heat and dampness can destroy some medicines.
If your doctor tells you to stop taking Imrest, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.
What it looks like
Imrest is an oval, white, film-coated tablet marked "Z|Z" on one side and "7.5" on the other. The tablets are scored.
Each pack contains 30 tablets.
The active ingredient in Imrest is zopiclone. Each tablet contains 7.5 mg of zopiclone.
The tablets also contain the following inactive ingredients:
- lactose anhydrous
- calcium hydrogen phosphate anhydrous
- maize starch
- magnesium stearate
- Opadry White Y-1-7000.
The tablets are gluten free.
Imrest is supplied in Australia by:
Alphapharm Pty Limited
(ABN 93 002 359 739)
Level 1, 30 The Bond
30-34 Hickson Road
Phone: (02) 9298 3999
Australian registration number:
Imrest - AUST R 99794, 99797
This leaflet was prepared on
24 July 2013.
CMI provided by MIMS Australia, December 2014