Interactions with cefuroxime

What are the interactions with cefuroxime?

Tell your doctor about all the medicines you are taking.

It is important that you tell your health professional about all the medicines you or anyone in your care is taking — including prescription, over-the-counter and complementary medicines (herbal, ‘natural’, vitamin and mineral supplements). This is because all medicines, including herbal and natural medicines, can cause side effects and may interact with other medicines.

Tell your doctor if you are taking:

  • warfarin (a medicine used to prevent blood clots): cefuroxime may increase the risk of bleeding. Your doctor may need to monitor your INR more often while you are taking cefuroxime.
  • probenecid (a medicine used to treat gout): taking cefuroxime with probenecid may increase the side effects of cefuroxime.
  • other antibiotics: certain other antibiotics (aminoglycosides) can cause kidney problems. Because cefuroxime can also sometimes affect the kidneys, taking these medicines together means there is a greater chance of serious kidney side effects.

Medicinewise tip

To check if your medicine contains this active ingredient, look on the packaging of your medicine for the active ingredient name, or use our Medicines Finder.

Can I drink alcohol if I am taking cefuroxime?

Drinking alcohol in moderation is unlikely to interact with cefuroxime or cause additional side effects.

Find out more about drinking alcohol when you are taking antibiotics .

Will cefuroxime affect my contraceptive?

Cefuroxime won’t affect your hormone contraceptive.

Rifampicin-like antibiotics (e.g. rifampicin and rifabutin) are the only types of antibiotic that are known to interact with some forms of hormone contraceptives, such as the combined contraceptive pill, making it less effective.

Find out more about antibiotics and contraception.

Phone for medicines information

Call NPS Medicines Line on 1300 MEDICINE (1300 633 424) to get information about your prescription, over-the-counter and complementary medicines (herbal, ‘natural’, vitamins and mineral supplements) from a pharmacist. Your call will be answered by healthdirect Australia.

  • Rossi S, ed. Australian Medicines Handbook [online]. Adelaide: AMH, July 2012.
  • Sweetman S, ed. Martindale: The complete drug reference [online]. London: Pharmaceutical Press (accessed 18 October 2011).
  • Antibiotic Expert Group. Therapeutic Guidelines: Antibiotic version 14; Cefuroxime. Melbourne: Therapeutic Guidelines Limited, 2012 (accessed 24 February 2012).