Ceftriaxone-AFT Powder for injection

Ceftriaxone-AFT Powder for injection is a brand of medicine containing the active ingredient ceftriaxone.

Find out more about active ingredients.

Consumer medicine information (CMI) leaflet

Developed by the pharmaceutical company responsible for this medicine in Australia, according to TGA regulations.


Ceftriaxone sodium equivalent to Ceftriaxone 500 mg, 1 g and 2 g, powder for injection

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about Ceftriaxone-AFT.

It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor will have considered risks of you being given Ceftriaxone-AFT against the benefits they expect it will have for you.

If you have any concerns or questions about being given this medicine, ask your doctor or pharmacist.

Keep this leaflet. You may need to read it again.

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What Ceftriaxone-AFT is used for

Ceftriaxone-AFT is an antibiotic used to treat infections in different parts of the body caused by bacteria. Ceftriaxone-AFT is also used to prevent infections before, during and after surgery. It will not work against infections caused by viruses such as colds and flus.

Ceftriaxone-AFT belongs to a group of antibiotics called cephalosporins. They work by killing the bacteria that are causing your infection or by stopping the bacteria from growing.

If you are not sure if you are uncertain why Ceftriaxone-AFT has been prescribed for you, talk to your doctor. They may have prescribed it for another reason.

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Before you are given Ceftriaxone-AFT

When you must not be given it

You must not use Ceftriaxone-AFT if you:

  • Have had an allergic reaction to Ceftriaxone-AFT or any other cephalosporin antibiotic
  • Have had an allergic reaction to any penicillin

Symptoms of allergic reactions include severe skin rash, itching, hives, dry skin, swelling of the face, lips, mouth, throat which may cause difficulty in swallowing or breathing, swelling of the hands, feet or ankles.

You may have an increased risk of being allergic to Ceftriaxone-AFT if you are allergic to penicillins.

Ceftriaxone-AFT should not be given to newborn infants if they need or are expected to need treatment with calcium containing intravenous solutions including intravenous nutrition.

Ceftriaxone-AFT should not be given to preterm newborns or newborns with certain liver disorders.

If you are uncertain if Ceftriaxone-AFT should be given to you, talk to your doctor.

Before you are given Ceftriaxone-AFT

You must tell your doctor if:

  • You have had any type of allergic reaction to any cephalosporin or penicillin medicines
  • You have had an allergy or over-reaction to lignocaine or other anaesthetic medicines (these substances may be used to dissolve Ceftroaxone-AFT before administration)
  • You have any allergies to any other medicines or other substances e.g. foods, preservatives, dyes
  • You have any other medical conditions including kidney disease, bowel problems (e.g. inflammation of the large bowel), diarrhoea associated with previous use of antibiotics or a previous intestinal infection with a bacteria called Clostridium difficile.
  • You are pregnant or intending to become pregnant
  • You are breast feeding or intending to breast feed

If you have not told your doctor about any of the above you must tell them before you are given Ceftriaxone-AFT.

Other Medicines

You must tell your doctor if you are taking any other medicines including any you may buy without a prescription from a pharmacy, supermarket or health food shop. Some medicines and Ceftriaxone-AFT may interfere with each other. These include:

  • chloramphenicol, vancomycin, aminoglycosides (medicines to treat infections),
  • fluconazole (a medicine used to treat fungal infections)
  • amsacrine (a medicine used to treat cancer).

These medicines may be affected by Ceftriaxone-AFT or may affect how well it works. You may need to take different amounts of your medicines. Your doctor will advise you.

Some antibiotics decrease the effectiveness of some contraceptive pills. Talk to your doctor about the need for additional contraception while using Ceftriaxone-AFT.

Your doctor or pharmacist will have more information on medicines to be careful with or avoid while being given Ceftriaxone-AFT.

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How Ceftriaxone-AFT is given

Ceftriaxone-AFT will be given by either a doctor or nurse.

Ceftriaxone-AFT can be given as either:

  • As a slow injection into a vein
  • As an injection into a large muscle

Ceftriaxone-AFT should not be mixed or administered with calcium-containing solutions even via different infusion lines.

Your doctor will decide what dose and for how long you will receive Ceftriaxone-AFT. It will depend on your infection and other factors such as your weight. For most infections Ceftriaxone-ADR is usually given once a day. The length of treatments is usually 4-14 days.

Sometimes only a single dose of Ceftriaxone-AFT is required for the treatment and prevention of certain infections.

If too much Ceftriaxone-AFT is given you may experience symptoms such as skin reactins, chills, diarrhoea, stomach upsets, headache or dizziness.

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While you are using Ceftriaxone-AFT

If the symptoms of your infection do not improve within a few days or if they become worse, tell your doctor.

If you get severe diarrhoea tell your doctor, nurse or pharmacist immediately even if occurs several weeks after Ceftriaxone-AFT has been stopped. Diarrhoea may mean you have a serious condition affecting your bowel. You may need urgent medical attention. Do not take any medicine to stop the diarrhoea without first checking with your doctor.

Tell you doctor if you get a sore or white furry mouth or tongue or if you get vaginal itching or discharge. You may have a fungal infection called thrush. Sometimes the use of Ceftriaxone-AFT may allow fungi to grow and the above symptoms to occur. Ceftriaxone-AFT will not work against fungi.

Tell your doctor if you become pregnant while using Ceftriaxone-AFT.

If you test your urine for sugar, make sure your doctor knows which type of test you use as Ceftriaxone-AFT may affect the test results.

If you are having any blood tests tell who ever is doing the tests that you are taking Ceftriaxone-AFT as Ceftriaxone-AFT may affect the results of some blood tests.

Complete blood counts should be done at regular intervals as Ceftriaxone-AFT may affect the results of some blood tests.

Tell all doctors, dentists and pharmacists who are treating you that you are using Ceftriaxone-AFT.

You must not:

  • Give Ceftriaxone to anyone else even if the seem to have the same condition as you
  • Use Ceftriaxone-ADR to treat other complaints unless your doctor says to

Be careful of driving or operating machinery until you know how Ceftriaxone-AFT affects you. Ceftriaxone-AFT generally does not cause any problems with you ability to drive or operate machinery. However Ceftriaxone-AFT may cause dizziness in some people.

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Side effects

Tell your doctor, nurse or pharmacist as soon as possible if you do not feel well while you are using Ceftriaxone-AFT. Ceftriaxone-AFT helps most people with infections but it may have unwanted side effects in a few people. All medicines have side effects. Sometimes these may be serious but most of the time they are not. You may need medical treatment if you get some of the side effects.

Ask your doctor or pharmacist to answer any questions you may have.

Tell you doctor or nurse if you notice any of the following and they worry you:

  • Oral thrush - white, furry, sore tongue and mouth
  • Vaginal thrush - sore and itchy vagina and/or discharge
  • A hard lump, swelling, pain or tenderness at the injection site
  • Diarrhoea, nausea or vomiting
  • Altered sense of taste
  • Headache, dizziness
  • Fast or irregular heartbeat

Tell you doctor immediately or go to the Emergency Department at your nearest hospital if you notice any of the following:

  • Severe skin rash, itching or hives
  • Red, peeling or dry skin
  • Swelling of the face, lips or tongue which may cause in difficulty swallowing or breathing, swelling of the hands, feet or ankles
  • Tiredness, headaches, being short of breath when exercising, dizziness, looking pale, yellowing of the skin and/or eyes
  • Severe diarrhoes that may contain blood or mucous, stomach pain and fever

These are serious side effects and you may need urgent medical attention. Serious side effects are rare.

Tell you doctor immediately if you notice any of the following particularly if they occur several weeks after stopping treatment with Ceftriaxone-AFT:

  • Severe abdominal (stomach) cramps
  • Watery and severe diarrhoea which may also be bloody
  • Fever in combination with one or both of the above

These are rare but serious side effects. You may have a serious condition affecting your bowel. You may need urgent medical attention. However this side effect is rare.

Do not take any medicines to stop the diarrhoea without first checking with your doctor.

This is not a full list of possible side effects. Some patients may experience other effects. Tell you doctor if you notice anything that is making you feel unwell.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

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You will only be given Ceftriaxone-AFT under medical supervision. It is unlikely that you will be given too much.

If you are given too much Ceftriaxone-AFT you may experience dizziness, headaches, stomach upset, chills, tingling or skin reactions. Your doctor will know what actions to take should you experience any signs of having received too much Ceftriaxone-AFT.

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Ceftriaxone-AFT will be stored in the pharmacy or on the hospital ward. It should be kept in a cool, dry place, protected from light and moisture at a temperature below 25°C.

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Ceftriaxone-AFT is a white to yellowish powder. It is dissolved before injection into a vein or muscle.

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Other ingredients

Ceftriaxone-AFT contains only Ceftriaxone sodium. If you are on a restricted sodium intake remind your doctor of this, so allowances can be made for the sodium content in Ceftriaxone-AFT as appropriate.

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If you want to know more

If you want to know more about Ceftriaxone-AFT, talk to your doctor or pharmacist.

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AFT Pharmaceuticals Pty Ltd
Level 1, 296 Burns Bay Road
Sydney, NSW 2066

Ceftriaxone-AFT 500 mg: AUST R 185099
Ceftriaxone-AFT 1 g: AUST R 185100
Ceftriaxone-AFT 2 g: AUST R 185101

Date: 20 February 2012

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CMI provided by MIMS Australia, August 2014  

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