NPS RADAR December 2005

Title Why read this
Anastrozole (Arimidex) for breast cancer in postmenopausal women Reports on PBS listing extension of anastrozole to include all postmenopausal women with hormone-dependent early breast cancer and compares anastrozole with tamoxifen.
Atorvastatin (Lipitor) for the management of lipid disorders Reviews use of atorvastatin for hyperlipidaemia, including comparison with simvastatin and pravastatin. Risk of myopathy and rhabdomyolysis is similar to that from other statins.
Buprenorphine transdermal patches (Norspan) for chronic severe pain Reviews use of buprenorphine skin patches for chronic severe non-cancer pain, including adverse effects, contraindications, and treatment of overdose.
Metformin/glibenclamide (Glucovance) for type 2 diabetes mellitus Reviews use of metformin/glibenclamide combination tablets for type 2 diabetes mellitus, including comparison with co-administered drugs and risk of hypoglycaemia.
NPS RADAR December 2005 NPS RADAR articles provide timely, independent, evidence-based assessment of new drugs, new PBS listings and research for health professionals.