Ocufen (Allergan Australia)
0.03% ophthalmic solution in 5 mL dropper bottles
Indication: inhibition of intra-operative miosis
Flurbiprofen is a derivative of the non-steroidal anti inflammatory drug ibuprofen. As it inhibits cyclo-oxygenase, it blocks the prostaglandin mediated pupillary constriction which can occur during ophthalmic surgery.
The eye drops are instilled before surgery. Patients may complain of burning or stinging, with 3% reporting severe discomfort. Although the drug is generally effective and safe, persistent mydriasis and increased bleeding, e.g. hyphaema, have been reported.