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Letter to the editor

Editor, – I refer to the Australian Adverse Drug Reactions Bulletin Vol. 15 No. 2 May 1996. In that issue, Table 1 'Reports of adverse hepatic reactions' is very sobering indeed. The ranitidine, diclofenac and phenytoin figures are particularly worrying. Could you publish the DDDs for these as well? Their % fatality for the number of reactions reported is higher than the top two (flucloxacillin and amoxycillin/potassium clavulanate).

John J. Byrne
General Practitioner
Ramsgate, N.S.W.


Editor's comment

The graphs below are produced with the assistance of both the Drug Utilization Sub-Committee of the Pharmaceutical Benefits Advisory Committee and the Adverse Drug Reactions Advisory Committee.

John J. Byrne

General Practitioner, Ramsgate, N.S.W.