Letters to the Editor
Rh D immunoglobulin
- Aust Prescr 2001;24:80-2
- 1 July 2001
- DOI: 10.18773/austprescr.2001.092
The Editorial Executive Committee welcomes letters, which should be less than 250 words. Before a decision to publish is made, letters which refer to a published article may be sent to the author for a response. Any letter may be sent to an expert for comment. When letters are published, they are usually accompanied in the same issue by their responses or comments. The Committee screens out discourteous, inaccurate or libellous statements. The letters are sub-edited before publication. Authors are required to declare any conflicts of interest. The Committee's decision on publication is final.
Editor, – Further to my article on the shortage of Rhesus D immunoglobulin (Aust Prescr 2000;23:36-8), a mini-dose of Rh D was marketed in May 2001. This has the dosage of 250 IU and should be offered to every Rh D negative woman with no preformed anti-D antibodies, for problems in the first twelve weeks of gestation. The indications usually include miscarriage, termination of pregnancy, ectopic pregnancy and chorionic villous sampling. The 250 IU dose is sufficient to prevent immunisation by a fetomaternal haemorrhage of 2.5 mL of red blood cells (5 mL of whole blood).
The introduction of the mini-dose is a significant achievement as currently a larger than necessary dose is being used for these first trimester indications. This will therefore allow a more efficient usage of the limited amount of anti-D.
A communication plan is being developed.
Australian Red Cross Blood Service - NSW