Pharmacovigilance in palliative care
Patients receiving palliative care are at high risk of adverse effects from drugs. As these effects can be difficult to distinguish from the symptoms of the terminal illness, harm from medicines is often not recognised.
Debra Rowett and David Currow, Aust Prescr 2014;37:204-9
Safe use of sodium valproate
Valproate is an anticonvulsant drug which is approved for use in epilepsy and bipolar disorder. It has also been used for neuropathic pain and migraine prophylaxis.
P-glycoprotein and its role in drug-drug interactions
Efflux transporters such as P-glycoprotein play an important role in drug transport in many organs. In the gut, P-glycoprotein pumps drugs back into the lumen, decreasing their absorption.
Andrew Finch and Peter Pillans, Aust Prescr 2014;37:137-9
Nutrients and herbal supplements for mental health
Some nutrient supplements and herbal medicines have supportive evidence for efficacy in some mental health disorders, other products do not.
Jerome Sarris, Aust Prescr 2014;37:90-3
Depression: tailoring initial treatment and re-examining the options
Depression treatment should be tailored to the individual patient. Meet two different patients with depression. How would you progress their initial care?
Appropriate use of dose administration aids
Dose administration aids can improve medicines management for some people. However, they have a number of limitations and are not suitable for all patients.
Rohan A Elliott, Aust Prescr 2014;37:46-50
Antimicrobials: surgical prophylaxis
Examine the role of antibiotic prophylaxis for patients undergoing surgical procedures.
New version released August 2019 to align with the revised and updated Therapeutic Guidelines: Antibiotic.
Type 2 diabetes: intensifying treatment
Two different patients with type 2 diabetes. How would you manage their diabetes care? A free case study from NPS.