Heart failure improvement measures

Creating the cohorts

 

Proportion of patients with heart failure who have an echocardiogram recorded (ever)

Definition

  • Proportion of patients* with heart failure who have an echocardiogram recorded (ever)  

Inclusion criteria

  • Patients with heart failure
  • Patients must have a record of being referred for or having received an echocardiogram (ever)

Exclusion criteria

  • N/A

Rationale

  • An echocardiogram is the single most useful investigation in heart failure, as it will confirm the diagnosis and inform future management strategies.1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

 

Proportion of patients with heart failure who have classification of heart failure recorded (ever): reduced ejection fraction (HFrEF) or preserved ejection fraction (HFpEF)

Definition

  • Proportion of patients* with heart failure who have classification of heart failure recorded (ever)

Inclusion criteria

  • Patients with heart failure
  • Patients must have a record of heart failure classification; either heart failure with reduced ejection fraction (HFrEF) or heart failure with preserved ejection fraction (HFpEF)

Exclusion criteria

  • N/A

Rationale

  • Identifying and recording the classification of heart failure (HFrEF or HFpEF) based on left ventricular ejection fraction (LVEF) is important as it guides effective treatment.1,7

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

Calculation instructions

Best Practice: HF classification

Date published : 17 June 2021

 

Proportion of patients with heart failure who have a GPMP/TCA or CVC program developed or reviewed in the last 12 months

Definition

  • Proportion of patients* with heart failure who have a GP Management Plan (GPMP) or Team Care Arrangement (TCA) or a Coordinated Veteran’s Care (CVC) program developed or reviewed in the last 12 months

Inclusion criteria

  • Patients with heart failure
  • Patients must have a record of a GPMP, or TCA or CVC program developed or reviewed in the last 12 months

Exclusion criteria

  • N/A

Rationale

  • Referral to a multidisciplinary heart failure management program is recommended in patients with heart failure associated with high-risk features, to decrease mortality and rehospitalisation.1

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

Calulation instructions

Best Practice: GPMP, TCA or CVA

Date published : 17 June 2021

 

Proportion of patients with heart failure who have been referred for an Home Medication Review (HMR) or Residential Medication Management Review (RMMR) in the last 12 months

Definition

  • Proportion of patients* with heart failure who have had a Home Medicines Review (HMR) or Residential Medication Management Review (RMMR) in the last 12 months

Inclusion criteria

  • Patients with heart failure
  • Patients must have a record of having an HMR/ RMMR developed or reviewed in the last 12 months

Exclusion criteria

  • N/A

Rationale

  • In patients with heart failure, HMRs were found to reduce the likelihood of hospitalisation by 46%. 8

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

Calculation instructions

Medical Director: HMR or RMMR

Date published : 17 June 2021

Best Practice: HMR or RMMR

Date published : 17 June 2021

 

Proportion of patients with heart failure vaccinated against influenza disease in the last 12 months

Definition

  • Proportion of patients* with heart failure vaccinated against influenza disease in the last 12 months

Inclusion criteria

  • Patients with heart failure
  • Patients must have a record of having received a vaccination against influenza disease in the last 12 months

Exclusion criteria

  • N/A

Rationale

  • Heart failure patients are at increased risk of respiratory infection and such infections are a major cause of decompensation. Patients should be vaccinated against influenza disease. There is evidence suggesting influenza vaccination may have a protective effect in heart failure. 1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

 

Proportion of patients with heart failure vaccinated against pneumococcal disease (ever)

Definition

  • Proportion of patients* with heart failure vaccinated against pneumococcal disease (ever)

Inclusion criteria

  • Patients with heart failure
  • Patients must have a record of having received a vaccination against pneumococcal disease (ever)

Exclusion criteria

  • N/A

Rationale

  • Heart failure patients are at increased risk of respiratory infection and such infections are a major cause of decompensation. Patients should be vaccinated against pneumococcal disease. There is evidence suggesting pneumococcal vaccination may have a protective effect in heart failure.1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

*Include all patients with a reference to heart failurewhether they qualify for the RACGP definition of an active patient or not.

 

Proportion of patients with HFrEF currently prescribed an ACE inhibitor, ARB or ARNI

Definition

  • Proportion of patients* with HFrEF currently prescribed an ACE inhibitor, ARB or an ARNI

Inclusion criteria

  • Patients with heart failure
  • Patients must have a record of being currently prescribed an ACE inhibitor, ARB or an ARNI

Exclusion criteria

  • Patients with a recorded classification of HFpEF

Rationale

  • An ACE inhibitor is recommended in all patients with HFrEF associated with a moderate or severe reduction in LVEF (LVEF less than or equal to 40%) to decrease mortality and decrease hospitalisation unless contraindicated or not tolerated. 1
  • An ARB is recommended if an ACE inhibitor is contraindicated or not tolerated to decrease the combined endpoint of cardiovascular mortality and hospitalisation for heart failure. 1
  • An ARNI is recommended as a replacement for an ACE inhibitor (or ARB) with a heart failure beta blocker (unless contraindicated), with or without an MRA, to decrease mortality and decrease hospitalisation.1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

 

Proportion of patients with HFrEF currently prescribed a heart failure beta blocker

Definition

  • Proportion of patients* with HFrEF currently prescribed a heart failure beta blocker

Inclusion criteria

  • Patients with heart failure
  • Patients must have a record of being currently prescribed a heart failure beta blocker

Exclusion criteria

  • Patients with a recorded classification of HFpEF

Rationale

  • A heart failure beta blocker is recommended in all patients with HFrEF associated with a moderate or severe reduction in LVEF (LVEF less than or equal to 40%) to decrease mortality and decrease hospitalisation unless contraindicated or not tolerated and once stabilised with no or minimal clinical congestion on physical examination.1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

 

Proportion of patients with HFrEF currently prescribed an MRA

Definition

  • Proportion of patients* with HFrEF currently prescribed an MRA

Inclusion criteria

  • Patients with HFrEF
  • Patients must have a record of being currently prescribed an MRA

Exclusion criteria

  • Patients with a recorded classification of HFpEF

Rationale

  • An MRA is recommended in all patients with HFrEF associated with a moderate or severe reduction in LVEF (LVEF less than or equal to 40%) unless contraindicated or not tolerated to decrease mortality and decrease hospitalisation.1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

 

Proportion of patients with HFrEF currently prescribed a combination of an ACE inhibitor, ARB or ARNI + heart failure beta blocker + MRA

Definition

  • Proportion of patients* with HFrEF currently prescribed an ACE inhibitor, ARB or ARNI + heart failure beta blocker + MRA

Inclusion criteria

  • Patients with HFrEF
  • Patients must have a record of being currently prescribed an ACE inhibitor, ARB or ARNI + heart failure beta blocker + MRA

Exclusion criteria

  • Patients with a recorded classification of HFpEF

Rationale

  • The cornerstone of pharmacotherapy for HFrEF comprises ACE inhibitor or angiotensin receptor blocker (ARBs) if the patient is intolerant of ACE inhibitors, followed by heart failure beta blockers then mineralocorticoid receptor antagonists (MRAs) then angiotensin receptor neprilysin inhibitors (ARNIs). 1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

ACE inhibitor: angiotensin-converting enzyme inhibitor, ARB: angiotensin receptor blocker, ARNI: angiotensin receptor neprilysin inhibitor, MRA: mineralocorticoid receptor antagonist 

 

Proportion of patients with HFrEF currently prescribed target dose of an ACE inhibitor, ARB or ARNI following 6 months commencement of medicine

Definition

  • Proportion of patients* with HFrEF currently prescribed an ACE inhibitor, ARB or ARNI at target dose following 6 months commencement of medicine

Inclusion criteria

  • Patients with HFrEF
  • Patients must be currently prescribed an ACE inhibitor, ARB or ARNI
  • Patients must be currently prescribed an ACE inhibitor, ARB or ARNI at target dose following 6 months commencement of medicine

Exclusion criteria

  • Patients with a recorded classification of HFpEF

Rationale

  • The combination of an ACE inhibitor + heart failure beta blocker + MRA would decrease mortality over 1-3 years 50-60%. Clinicians should aim for the target doses used in the RCT that showed the benefit of the medicines. An ARNI has been shown to further decrease mortality compared to an ACE inhibitor in patients with persistent HFrEF despite current best practice (including a beta blocker and ACE inhibitor or ARB with or without an MRA).1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

For information about target doses visit: Clinical fact sheet: pharmacological management of chronic heart failure with reduced ejection fraction (HFrEF).

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

 

Proportion of patients with HFrEF currently prescribed a heart failure beta blocker at target dose following 6 months commencement of medicine

Definition

  • Proportion of patients* with HFrEF currently prescribed a heart failure beta blocker at target dose following 6 months commencement of medicine

Inclusion criteria

  • Patients with heart failure
  • Patients must be currently prescribed a heart failure beta blocker
  • Patients must be currently prescribed target dose following 6 months commencement of medicine

Exclusion criteria

  • Patients with a recorded classification of HFpEF

Rationale

  • The combination of an ACE inhibitor + heart failure beta blocker + MRA would decrease mortality over 1-3 years 50-60%. Clinicians should aim for the target doses used in the RCT that showed the benefit of the medicines.1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

For information about target doses visit: Clinical fact sheet: pharmacological management of chronic heart failure with reduced ejection fraction (HFrEF).

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

 

Proportion of patients with heart failure reviewed within 2 weeks following hospital discharge

Definition

  • Proportion of patients* with heart failure reviewed within 2 weeks following hospital discharge

Inclusion criteria

  • Patients with heart failure
  • Patients must have been hospitalised for heart failure
  • Patients must have been reviewed within 2 weeks following hospital discharge

Exclusion criteria

  • N/A

Rationale

  • Prospective studies and regulatory data have shown that the most vulnerable period for patients with heart failure is within the first few weeks post- hospital discharge. Ideally these patients should be reviewed within the first 7-14 days of hospital discharge. 1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

 

Proportion of patients with heart failure currently prescribed medicines that can worsen heart failure

Definition

  • Proportion of patients* with heart failure currently prescribed a non-steroidal anti-inflammatory drug (NSAID), cyclo-oxygenase inhibitor (COX-2 inhibitor), diltiazem or verapamil, oral corticosteroid, tricyclic antidepressant (TCA).

Inclusion criteria

  • Patients with heart failure
  • Patients must have a record of a NSAID or COX-2 inhibitor or diltiazem or verapamil or an oral corticosteroid or a TCA in their current medicine list.

Exclusion criteria

  • N/A

Rationale

  • Non-steroidal anti-inflammatory drugs (NSAIDs), cyclo-oxygenase inhibitors (COX-2 inhibitor), diltiazem, verapamil, oral corticosteroid and tricyclic antidepressants (TCAs) can worsen symptoms in patients with heart failure.1

Calculation instructions

  • NPS MedicineWise is working with others in the primary care data space to develop assistance in calculating this measure.
  • Data audit tools extract and analyse practice-level data. Your PHN should be your point of contact for advice and training.

*Include all patients with a reference to heart failure whether they qualify for the RACGP definition of an active patient or not.

 

References

  1. Atherton JJ, Sindone A, De Pasquale CG, et al. National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Guidelines for the prevention, detection, and management of heart failure in Australia 2018. Heart Lung Circ 2018;27:1123-208.
  2. Chan YK, Tuttle C, Ball J, et al. Current and projected burden of heart failure in the Australian adult population: a substantive but still ill-defined major health issue. BMC Health Serv Res 2016;16:501.
  3. National Heart Foundation of Australia. Clinical fact sheet - diagnosis and classification of heart failure. Sydney: NHF, 2019 (accessed 22 April 2020).
  4. Australian Government. Australian Institute of Health and Welfare National morbidity database hospitalisations 2018-19. Canberra: AIHW, 2020 (accessed 22 April 2021).
  5. Al-Omary MS, Davies AJ, Evans TJ, et al. Mortality and readmission following hospitalisation for heart failure in Australia: A systematic review and meta-analysis. Heart Lung Circ 2018;27:917-27.
  6. Australian Commission on Safety and Quality in Healthcare. Second Australian atlas of healthcare variation Sydney: ACSQH, 2017 (accessed 20 April 2020).
  7. De Pasquale CG, Audehm R. Diagnosis of heart failure. Medicine Today 2019;20:11-6.
  8. Australian Government Department of Veteran's Affairs. Veteran's Mates 2004-2010- Veterans' medicines advice and therapeutic educational services program. Adelaide: University of South Australia - Quality Use of Medicines and Pharmacy Research Centre, 2011 (accessed 18 March 2021).