SUMMARY CMI
APO-METOCLOPRAMIDE
Consumer Medicine Information (CMI) summary
The full CMI on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist.
1. Why am I using APO-Metoclopramide?
APO-Metoclopramide contains the active ingredient metoclopramide hydrochloride (as monohydrate). APO-Metoclopramide is used to treat nausea and vomiting caused by infectious diseases, kidney disease, childbirth, other medications, cancer, or following surgery, chemotherapy, or radiation treatment.
For more information, see Section 1. Why am I using APO-Metoclopramide? in the full CMI.
2. What should I know before I use APO-Metoclopramide?
Do not use it if you have ever had an allergic reaction to APO-Metoclopramide or any of the ingredients listed at the end of the CMI. Talk to your doctor if you have any other medical conditions, take any other medicines, or are pregnant or plan to become pregnant or are breastfeeding.
For more information, see Section 2. What should I know before I use APO-Metoclopramide? in the full CMI.
3. What if I am taking other medicines?
Some medicines may interfere with APO-Metoclopramide and affect how it works.
A list of these medicines is in Section 3. What if I am taking other medicines? in the full CMI.
4. How do I use APO-Metoclopramide?
- Adults 20 years and over: take 1 tablet every 8 hours.
- Adolescents: 15 to 19 years: take ½ to 1 tablet every 8 hours.
More instructions can be found in Section 4. How do I use APO-Metoclopramide? in the full CMI.
5. What should I know while using APO-Metoclopramide?
Things you should do |
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Things you should not do |
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Driving or using machines |
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Drinking alcohol |
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Looking after your medicine |
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For more information, see Section 5. What should I know while using APO-Metoclopramide? in the full CMI.
6. Are there any side effects?
Common side effects include drowsiness, tiredness, restlessness, dizziness, headache, bowel irregularities, insomnia, anxiety and agitation.
Serious side effects include uncontrolled or repeated movements, (e.g., sucking or smacking of the lips, darting of the tongue, chewing movements, uncontrolled movements of the arms or legs), fast heartbeat, depression, or swelling of hands, ankles, or feet.
For more information, including what to do if you have any side effects, see Section 6. Are there any side effects? in the full CMI.
FULL CMI
APO-METOCLOPRAMIDE
Active ingredient(s): metoclopramide hydrochloride (as monohydrate)
Consumer Medicine Information (CMI)
This leaflet provides important information about using APO-Metoclopramide. You should also speak to your doctor or pharmacist if you would like further information or if you have any concerns or questions about using APO-Metoclopramide.
Where to find information in this leaflet:
1. Why am I using APO-Metoclopramide?
2. What should I know before I use APO-Metoclopramide?
3. What if I am taking other medicines?
4. How do I use APO-Metoclopramide?
5. What should I know while using APO-Metoclopramide?
6. Are there any side effects?
7. Product details
1. Why am I using APO-Metoclopramide?
APO-Metoclopramide contains the active ingredient metoclopramide hydrochloride (as monohydrate). APO-Metoclopramide works by blocking the action of a chemical in the brain which causes nausea and vomiting. It also acts in the stomach and upper intestine to increase muscle contractions.
APO-Metoclopramide is used in adults over 20 years and over:
- to treat nausea and vomiting caused by infectious diseases, kidney disease, childbirth, other medications, cancer, or following surgery, chemotherapy, or radiation treatment.
- To activate stomach contractions in conditions where there is a need to encourage normal passage of food through the stomach and intestines.
- With X-rays to help diagnose problems of the stomach and/or intestines
- To help with passing tubes into the intestine.
In young adults aged 15 – 19 years to:
- Treat severe vomiting of known cause or following chemotherapy or radiation treatment.
- Help with passage tubes into the intestine.
2. What should I know before I use APO-Metoclopramide?
Warnings
Do not use APO-Metoclopramide if:
- you are allergic to metoclopramide hydrochloride (as monohydrate), or any of the ingredients listed at the end of this leaflet.
- Always check the ingredients to make sure you can use this medicine.
- have active bleeding from the stomach and/or digestive tract.
- have a blockage of the stomach and/or digestive tract.
- have had recent surgery of the stomach and/or digestive tract.
- have phaeochromocytoma (an adrenaline producing tumour of the adrenal gland).
- have epilepsy (fits or seizures).
- take other medication such as antipsychotic/ neuroleptic medication and certain antidepressants that can cause movement disorders.
Check with your doctor if you:
- have any other medical conditions including:
- Parkinson's disease
- liver or kidney problems
- high blood pressure
- asthma - take any medicines for any other condition.
During treatment, you may be at risk of developing certain side effects. It is important you understand these risks and how to monitor them. See additional information under Section 6. Are there any side effects?
Pregnancy and breastfeeding
Check with your doctor if you are pregnant or intend to become pregnant.
Talk to your doctor if you are breastfeeding or intend to breastfeed.
Use in children
Do not give APO-Metoclopramide to children less than 15 years old.
3. What if I am taking other medicines?
Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop.
Some medicines and APO-Metoclopramide may interfere with each other. These include:
- Tranquilizers or anti-anxiety medications
- Strong pain relievers (e.g., codeine or morphine)
- Sedatives or sleeping medications.
- Atropine-like medications (e.g., some cold preparations, relief of stomach cramps or spasms, travel sickness)
- Tetracycline antibiotics
- Paracetamol
- Levodopa
- Digoxin
Check with your doctor or pharmacist if you are not sure about what medicines, vitamins or supplements you are taking and if these affect APO-Metoclopramide.
4. How do I use APO-Metoclopramide?
How much to use
Follow the instructions provided and use APO-Metoclopramide until your doctor tells you to stop.
Do not exceed the prescribed dose.
- Adults 20 years and over - 1 tablet every 8 hours.
- Adolescents: 15 to 19 years - ½ to 1 tablet every 8 hours.
- Swallow the tablets with a full glass of water.
- If required, the tablets can be broken in half (along with the break-line).
- Take your tablet at least 30 minutes before meals.
If you are taking APO-Metoclopramide before a diagnostic procedure your doctor will give you your dose.
This will usually be a single dose of 1-2 tablets depending on your age.
If you have significant kidney or liver impairment your doctor may prescribe a lower dose.
How long to take APO-Metoclopramide
Your doctor will advise you how long to take APO-Metoclopramide. The maximum recommended treatment duration is 5 days.
If you forget to use APO-Metoclopramide
APO-Metoclopramide should be used regularly at the same time each day.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Do not take a double dose to make up for the dose you missed.
If you use too much APO-Metoclopramide
If you think that you have used too much APO-Metoclopramide, you may need urgent medical attention.
Symptoms of an overdose may include drowsiness, confusion, dizziness, headache, agitation, nausea, vomiting, constipation, tremor, twitching or uncontrolled spasm of muscles.
You should immediately:
- phone the Poisons Information Centre
(by calling 13 11 26), or - contact your doctor, or
- go to the Emergency Department at your nearest hospital.
You should do this even if there are no signs of discomfort or poisoning.
5. What should I know while using APO-Metoclopramide?
Things you should do
Call your doctor if:
- nausea and vomiting persist.
- you become pregnant while taking APO-Metoclopramide.
If you are going to have surgery, tell the surgeon or anaesthetist that you are taking APO-Metoclopramide. It may affect other medicines used during surgery.
Remind any doctor, dentist, or pharmacist you visit that you are using APO-Metoclopramide.
Things you should not do
- Do not take this medicine to treat any other conditions unless your doctor tells you to.
- Do not give your medicine to anyone else, even if they have the same condition as you.
Driving or using machines
Be careful before you drive or use any machines or tools until you know how APO-Metoclopramide affects you.
APO-Metoclopramide may cause dizziness, light-headedness, tiredness, or drowsiness in some people.
If you have any of these symptoms, do not drive, operate machinery, or do anything else that could be dangerous.
Drinking alcohol
Tell your doctor if you drink alcohol.
Be careful when drinking alcohol when you are taking this medicine.
If you drink alcohol, it may make you sleepy.
Looking after your medicine
- Keep your medicine in its original packaging until it is time to take it.
- If you take your medicine out of its original packaging it may not be kept well.
- Keep your medicine in a cool dry place where the temperature will stay below 25°C.
Follow the instructions in the carton on how to take care of your medicine properly.
Store it in a cool dry place away from moisture, heat, or sunlight; for example, do not store it:
- in the bathroom or near a sink, or
- in the car or on windowsills.
Heat and dampness can destroy some medicines.
Keep it where young children cannot reach it.
A locked cupboard at least one-and-a half-meters above the ground is a good place to store medicines.
When to discard your medicine
If your doctor tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the remaining medicine safely.
Getting rid of any unwanted medicine
If you no longer need to use this medicine or it is out of date, take it to any pharmacy for safe disposal.
Do not use this medicine after the expiry date.
6. Are there any side effects?
All medicines can have side effects. If you do experience any side effects, most of them are minor and temporary. However, some side effects may need medical attention.
See the information below and, if you need to, ask your doctor or pharmacist if you have any further questions about side effects.
Less serious side effects
Less serious side effects | What to do |
| Speak to your doctor if you have any of these less serious side effects and they worry you. |
Serious side effects
Serious side effects | What to do |
| Call your doctor straight away, or go straight to the Emergency Department at your nearest hospital if you notice any of these serious side effects. |
Very Serious side effects
Very serious side effects | What to do |
| Call your doctor straight away, or go straight to the Emergency Department at your nearest hospital if you notice any of these serious side effects. |
Tell your doctor or pharmacist if you notice anything else that may be making you feel unwell.
Other side effects not listed here may occur in some people.
Reporting side effects
After you have received medical advice for any side effects you experience, you can report side effects to the Therapeutic Goods Administration online at www.tga.gov.au/reporting-problems. By reporting side effects, you can help provide more information on the safety of this medicine.
Always make sure you speak to your doctor or pharmacist before you decide to stop taking any of your medicines.
7. Product details
This medicine is only available with a doctor's prescription.
What APO-Metoclopramide contains
Active ingredient (main ingredient) | Metoclopramide hydrochloride (as monohydrate) |
Other ingredients (inactive ingredients) | Maize starch Pregelatinized maize starch Microcrystalline cellulose Colloidal anhydrous silica Stearic acid Hypromellose Macrogol 6000 Titanium dioxide Purified talc |
Potential allergens | N/A |
This medicine is gluten free, lactose free, sucrose free, tartrazine free and free of other azo dyes.
Do not take this medicine if you are allergic to any of these ingredients.
What APO-Metoclopramide looks like
10 mg tablets:
APO-Metoclopramide 10 mg tablets are white to off-white, circular, biconvex film-coated tablets with break line on both sides (Aust R 196502).
Available in blister packs of 25 and 100.
Not all strengths, pack types and/or pack sizes may be available.
Who distributes APO-Metoclopramide?
Arrotex Pharmaceuticals Pty Ltd
15-17 Chapel Street
Cremorne VIC 3121
Australia
Tel: 1800 195 055
Web: www.arrotex.com.au
This leaflet was prepared in December 2024.
Published by MIMS February 2025