Non-pharmacological measures such as hot/cold packs or rest, followed by paracetamol alone, should be considered first for the management of mild acute pain.7
Paracetamol/ibuprofen combination medicines have a place in therapy for the short-term management of moderate pain.4,7
The dosing instructions specify that these combinations should not be used for more than a few daysc at a time unless on medical advice, in which case the ongoing need for treatment should be reviewed regularly.1,2
While paracetamol and ibuprofen can both be purchased OTC, neither is free of safety risks and the same precautions apply to these active ingredients when used in combination.
Paracetamol is generally well tolerated when used at recommended doses but overdose can, on rare occasions, lead to liver failure.7-9
Ibuprofen should be used with caution in older people, those with kidney disease, a history of peptic ulcer disease, asthma, hypertension or heart failure.1,2,7,10
In late 2016 the Therapeutic Goods Administration issued a safety advisory for non-aspirin NSAIDs such as ibuprofen, advising that use ‘is known to be associated with an increase in the risk of miscarriage, particularly when taken close to the time of conception.’11
- 3 days for adults and 2 days for adolescents (12–17 years) for Nuromol.