SUMMARY CMI

LITHICARB

Consumer Medicine Information (CMI) summary

The full CMI on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist.

1. Why am I using Lithicarb?

Lithicarb contains the active ingredient lithium carbonate. Lithicarb is used to treat and prevent episodes of a condition called manic depressive or bipolar disorder, in which there are sustained mood swings either up (manic) or down (depression).

It is also used in the treatment of schizo-affective illness and chronic schizophrenia

For more information, see Section 1. Why am I using Lithicarb? in the full CMI.

2. What should I know before I use Lithicarb?

Do not use if you have ever had an allergic reaction to Lithicarb or any of the ingredients listed at the end of the CMI.

Talk to your doctor if you have any other medical conditions, take any other medicines, or are pregnant or plan to become pregnant or are breastfeeding.

For more information, see Section 2. What should I know before I use Lithicarb? in the full CMI.

3. What if I am taking other medicines?

Some medicines may interfere with Lithicarb and affect how it works.

A list of these medicines is in Section 3. What if I am taking other medicines? in the full CMI.

4. How do I use Lithicarb?

• Your doctor will tell you how much Lithicarb to take.
• Lithicarb should be taken with a meal or snack to prevent stomach upset.
• Your doctor however may have prescribed Lithicarb for another purpose.

More instructions can be found in Section 4. How do I use Lithicarb? in the full CMI.

5. What should I know while using Lithicarb?

For more information, see Section 5. What should I know while using Lithicarb? in the full CMI.

6. Are there any side effects?

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Lithicarb. Some mild side effects include stomach upset with mild nausea and diarrhoea, feeling dizzy, muscle weakness, fluid retention, unusual tiredness and thirst. Some serious side effects include irregular heartbeat, passing large amounts of urine, confusion, staggering and slurred speech and severe stomach cramps or pain.

For more information, including what to do if you have any side effects, see Section 6. Are there any side effects? in the full CMI.

FULL CMI

LITHICARB

Active ingredient(s): Lithium carbonate

Consumer Medicine Information (CMI)

This leaflet provides important information about using Lithicarb. You should also speak to your doctor or pharmacist if you would like further information or if you have any concerns or questions about Lithicarb.

Where to find information in this leaflet:

1. Why am I using Lithicarb?
2. What should I know before I use Lithicarb?
3. What if I am taking other medicines?
4. How do I use Lithicarb?
5. What should I know while using Lithicarb?
6. Are there any side effects?
7. Product details

1. Why am I using Lithicarb?

Lithicarb contains the active ingredient lithium carbonate. Lithicarb is a powerful mood stabiliser, however the exact way that lithium works to stabilize a person's mood is not known. It helps you have more control over your emotions and helps you cope better.

Lithicarb is used to both treat and prevent episodes of a condition called manic-depressive or bipolar disorder, in which there are sustained mood swings either up (manic) or down (depressive).

It is also used in the treatment of schizo-affective illness and chronic schizophrenia.

Your doctor, however, may have prescribed Lithicarb for another purpose.

2. What should I know before I use Lithicarb?

Warnings

Do not use Lithicarb if:

• You are allergic to lithium carbonate, or any of the ingredients listed at the end of this leaflet.
• Some symptoms of an allergic reaction include shortness of breath, wheezing or difficulty breathing, swelling of the face, lips or tongue or other parts of the body, rash, itching or hives on the skin.
• Always check the ingredients to make sure you can use this medicine.
• You have or have had severe heart or kidney disease, low activity of the adrenal gland (e.g. Addison's disease), an underactive thyroid gland or low levels of sodium in your body (e.g. if you are dehydrated or on a low salt diet)
• It is after the expiry date printed on the pack. The packaging is torn or shows signs of tampering.

Check with your doctor if you:

Have any of the following medical conditions

• Conditions for which you take diuretics (fluid tablets)
• Vomiting or diarrhoea
• Two infections occurring at the same time
• Brugada syndrome or someone in your family has Brugada syndrome (a genetic disease that affects the heart.

Do not take diuretics (water pills) medication that increases urination without first consulting your doctor.

Take any medicines for any other condition.

A medical examination and some laboratory tests are usually performed before you begin therapy with Lithicarb. They are usually repeated at regular intervals while you continue to take this medicine.

If you have not told your doctor about any of the above, tell them before you start taking Lithicarb. During treatment, you may be at risk of developing certain side effects. It is important you understand these risks and how to monitor for them. See additional information under Section 6. Are there any side effects?

Pregnancy and breastfeeding

Do not take Lithicarb if you are pregnant, plan to become pregnant or are breastfeeding unless you and your doctor have discussed the risks and benefits involved.

If you have not told your doctor about any of the above, tell them before you start taking Lithicarb.

Use in Children

Do not give Lithicarb to children.

This medicine is not recommended for children as there is no specific information about such use.

Use in Elderly

Elderly patients may be more sensitive to the effects or side effects of this medicine. If you are elderly you need to watch carefully for signs of side effects or lithium toxicity. Elderly patients may require a lower dosage than younger patients.

3. What if I am taking other medicines?

Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop.

Lithicarb interacts with many other medicines. This can cause a change in the blood levels of either the lithium or of the other medicine, increasing the chance of side effects or lithium toxicity.

Lithium toxicity may occur if the level of lithium in your blood becomes too high. If you are taking a medication which interacts with Lithicarb your blood lithium levels will need to be monitored closely.

Some medicines in common use that may interfere with Lithicarb include:

• Medicines for removal of fluid (diuretics)
• Some medicines for high blood pressure and other heart drug (e.g. captopril, enalapril, calcium channel blockers, methyldopa, Atacand and Cozaar)
• Some types of tranquillisers (e.g. diazepam)
• Some medicines for depression (e.g. fluoxetine, imipramine)
• Some medicines for arthritis or pain (e.g. indomethacin, piroxicam, celecoxib)
• Appetite suppressants
• Some medicines for epilepsy (e.g. carbamazepine and phenytoin)
• Medicines for epilepsy (e.g. carbamazepine and phenytoin)
• Medicines used to treat respiratory illness (e.g. theophylline)
• Medicines that change the acidity of the urine (e.g. sodium bicarbonate)
• Medicines used to treat certain mental health conditions (e.g. haloperidol)
• Ziprasidone, which can interact with lithium to affect the heart
• Medicines containing steroids (e.g. prednisolone)
• Medicines used to treat glaucoma (e.g. acetazolamide)
• Medicines used to treat skin disorders (e.g. urea)
• Some antibiotics (e.g. metronidazole).

These medicines may be affected by Lithicarb or may affect how well it works. You may need to take different amounts of your medicine or you may need to take different medicines.

Check with your doctor or pharmacist if you are not sure about what medicines, vitamins or supplements you are taking and if these affect Lithicarb.

If you have not told your doctor about any of these things, tell them before you take Lithicarb.

4. How do I use Lithicarb?

How much to take / use

• Your doctor will tell you how much Lithicarb to take.
• Follow the instructions provided and use Lithicarb until your doctor tells you to stop.
• The dose required to reach an effective level in the blood varies between individuals. For this reason the dose needs to be adjusted to suit you.
• In the early stages of your treatment your doctor will arrange several blood tests to establish your blood level of lithium and the dose of Lithicarb that is correct for you. You will need to have regular blood tests to monitor your blood lithium level.
• Your body's requirements of lithium may change and it may be necessary for your doctor to change the amount of Lithicarb taken to effectively control your mood swings.

When to take / use Lithicarb

• Lithicarb should be taken with a meal or snack to prevent stomach upset.
• In order for Lithicarb to work properly, spread out the recommended dose evenly throughout the day. This will help keep the amount of lithium in your blood constant.
• Do not miss any doses and do not stop taking the medicine even if you feel better.
• Missing doses may make your symptoms worse.

How long to take it

• Continue taking Lithicarb for as long as your doctor tells you.
• Lithicarb is not a cure. To control mood swings you may need to take it for a long period of time. Only after several months or even years can you and your doctor decide whether taking it is still necessary.
• To maximise its effectiveness it is important that you take the prescribed dose of Lithicarb regularly.

What to Expect:

• When you start taking Lithicarb your mood swings should become less frequent, less severe and less prolonged.
• Sometimes it must be taken for one to several weeks before you begin to feel better. However, it may take six to twelve months before the full benefits of lithium therapy become apparent. To maximise its effectiveness it is important that you take the prescribed dose of Lithicarb regularly.

If you forget to use Lithicarb

Lithicarb should be used regularly at the same time each day. If you miss your dose at the usual time and it is

• More than two hours before your next dose is due: Take it straight away, then continue as you normally would.
• Less than two hours to your next dose: Skip the dose you have missed but be sure to take the next dose when you are meant to.

Do not take a double dose to make up for the dose you missed.

If you use too much Lithicarb

If you think that you or anyone else have used too much Lithicarb, you may need urgent medical attention.

Symptoms of overdose include vomiting, nausea, abdominal pain, anorexia, occasionally mild diarrhoea, giddiness, tremor, ataxia, slurring speech, myoclonus, twitching, asthenia, depression and renal symptoms. In serious cases, fits (convulsions) and coma may occur.

You should immediately:

• phone the Poisons Information Centre
  (by calling 13 11 26), or
• contact your doctor, or
• go to the Emergency Department at your nearest hospital.

You should do this even if there are no signs of discomfort or poisoning.

5. What should I know while using Lithicarb?

Things you should do

When you first start taking Lithicarb, you may require two or more blood tests a week. Once your lithium levels are stable, you should need tests about 4 times a year to check that your blood lithium level is stable. If your Lithicarb dose is changed or if you have signs of lithium toxicity you may need more frequent blood tests.

The blood test must be done twelve hours after a dose, before you have taken your morning tablets. Take Lithicarb exactly as your doctor has prescribed.

Tell your doctor if you are taking medicines to treat epilepsy or seizures (e.g. carbamazepine and phenytoin). This is because when it is taken with Lithicarb, it may cause a rare serious brain condition called encephalopathic syndrome. The symptoms include weakness, lethargy, fever, confusion and shaking. Monitor closely for these symptoms and visit your doctor immediately if you experience these.

If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Lithicarb.

Tell your doctor immediately if you become pregnant while taking Lithicarb.

Tell all doctors, dentists and pharmacists who are treating you, that you are taking Lithicarb.

Lithicarb should always be taken with care and under your doctor's supervision because serious side effects may occur if the level of lithium in your blood becomes too high (lithium toxicity). This can happen if you are taking too much lithium or if there are major changes to your normal health or lifestyle.

There are a number of things you can do during therapy with Lithicarb to help prevent lithium toxicity, such as:

• maintain a normal diet with adequate salt and fluid
• consult your doctor before you make any dietary changes
• avoid reducing your salt intake
• avoid heavy exercise which may lead to excessive sweating and water loss
• take extra care in hot weather by limiting exposure to the heat. Drink plenty of fluids to avoid becoming dehydrated.
• watch for signs of lithium toxicity if you have an infection or have symptoms such as fever, vomiting or diarrhoea
• watch for signs of lithium toxicity if your regular dose of Lithicarb is increased or changed or if you start taking another medication

If you are not aware of the signs of lithium toxicity you should ask your doctor.

You and your family should be able to recognise the signs of lithium toxicity and know what to do if they occur.

Things you should not do

Do not give this medicine to anyone else, even if they have the same condition as you.

Do not stop taking Lithicarb suddenly unless advised by your doctor.

If you stop taking it suddenly your mood swings may return. If you want to stop taking Lithicarb, your doctor will tell you how to do it gradually over several weeks or months.

Driving or using machines

Be careful before you drive or use any machines or tools until you know how Lithicarb affects you.

This medicine may cause drowsiness, poor co-ordination and blurred vision in some patients, especially when you first start to take it. Make sure you know how you react to it before you drive a car, operate machinery, or do anything else that could be dangerous.

Drinking alcohol

Be careful when drinking alcohol while you are taking Lithicarb.

If you drink alcohol while you are taking it side effects such as drowsiness may become worse.

Looking after your medicine

Keep Lithicarb tablets in a cool dry place where the temperature stays below 30°C.

Store it in a cool dry place away from moisture, heat or sunlight; for example, do not store it:

• in the bathroom or near a sink, or
• in the car or on window sills.

Heat and dampness can destroy some medicines.

Keep it where young children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Getting rid of any unwanted medicine

If your doctor advises you no longer need to use this medicine or it is out of date, take it to any pharmacy for safe disposal.

Do not use this medicine after the expiry date.

6. Are there any side effects?

All medicines can have side effects. If you do experience any side effects, most of them are minor and temporary. However, some side effects may need medical attention.

See the information below and, if you need to, ask your doctor or pharmacist if you have any further questions about side effects.

Less serious side effects

When Lithicarb is taken for long periods of time the following side effects can occur:

• Thyroid changes (goitre)
• Weight gain
• Mild forgetfulness
• Hair thinning

Your doctor may suggest some dietary or lifestyle changes to help reduce these effects.

Serious side effects

Tell your doctor or pharmacist if you notice anything else that may be making you feel unwell.

Other side effects not listed here may occur in some people.

Reporting side effects

After you have received medical advice for any side effects you experience, you can report side effects to the Therapeutic Goods Administration online at www.tga.gov.au/reporting-problems. By reporting side effects, you can help provide more information on the safety of this medicine.

Always make sure you speak to your doctor or pharmacist before you decide to stop taking any of your medicines.

7. Product details

This medicine is only available with a doctor's prescription.

What Lithicarb contains

Do not take this medicine if you are allergic to any of these ingredients.

Lithicarb tablets do not contain sucrose, tartrazine or any other azo dyes.

What Lithicarb looks like

Lithicarb are white to off-white oval-shaped bevel edged film coated tablets, with breakline on one side and plain on the other.

The tablets are available in bottles of 200.

Who distributes Lithicarb

Aspen Pharmacare Australia Pty Ltd
34-36 Chandos St
St Leonards NSW 2065
Australia

AUST R 49625

This leaflet was prepared in October 2022.

Published by MIMS March 2023

1 Name of Medicine

Lithium carbonate.

2 Qualitative and Quantitative Composition

White to off-white oval-shaped bevel edged film coated tablets, with breakline on one side and plain on the other side.
Each Lithicarb tablet contains 250 mg of the active lithium carbonate.

List of excipients with known effect.

3 Pharmaceutical Form

See Section 2 Qualitative and Quantitative Composition.

4 Clinical Particulars

4.1 Therapeutic Indications

The indications for lithium therapy may be summarised as follows:
It is given for mania, both as treatment and prophylaxis; manic depressive (bipolar) illness, both as treatment and as prophylaxis; it is less effective in depressive swings. In recurrent endogenous (unipolar) depressive illness, it is highly effective as prophylaxis in a number of cases, and is probably useful as treatment, especially if there is a family history of manic depressive illness and response to lithium.
In some cases of schizoaffective illness and so called chronic schizophrenia it is dramatically effective. Those in the latter category who do respond have frequently had affective symptoms at some time. It is used in character or personality disorders in young people with clear evidence of cyclothymia.
Lithium should not be prescribed until it is certain that the manic depressive swings are established and the course of the disease certain. If the patient has two effective swings in one year, perhaps in opposite directions, and associated with a positive family history, it should certainly be seriously considered. With 3 episodes in two years, there is no doubt it should be given. As a general rule, it should be prescribed and therapeutic response assessed, satisfactory maintenance dosage determined, side and toxic effects and associated precautions discussed with the patient and relatives and blood levels monitored, only under specialist supervision except perhaps in isolated areas. A major management problem also, is that there are relatively narrow distances between the therapeutic and toxic dosages and blood levels. For these reasons treatment is preferably commenced on an inpatient basis, so that the patient is under appropriate observation.

4.2 Dose and Method of Administration

The dosage of lithium depends upon whether it is being used for an acute condition or for prophylactic purposes.
In acute mania, a program has been established aimed at obtaining high serum levels as rapidly as is safely possible. Some patients take up to 2 weeks to respond, and during this time they are difficult to manage.
Doses of up to 1.75 g daily may be given in divided doses, and workers have recommended the following dosage:
Day 1: 500 to 1,000 mg in divided doses.
Day 2: 1,250 to 1,750 mg in divided doses.
Day 3: 1,500 to 2,000 mg in divided doses.
This should give blood levels of between 0.8 to 1.6 mmol/L, but the serum level must be checked. It is most important not to exceed a level of 2 mmol/L. When remission has been produced in 7 to 14 days, dosage is reduced in stepwise fashion to a dose sufficient to maintain the blood level within the therapeutic range, usually 500 mg to 1 g/day, taken in one or two doses. When remission is achieved, it is important to maintain satisfactory basal blood levels. Lithium should be taken with food, as it causes less nausea than on an empty stomach.

Frequency of blood level determinations.

Base or steady-state blood levels.

4.3 Contraindications

Patients with significant cardiovascular or renal disease.
Frank hypothyroidism.
Conditions associated with hyponatremia, for example: Addison's disease, dehydrated or severely debilitated patients, patients on low sodium diets.
Diuretics should not be used during lithium therapy without appropriate dosage adjustment.
Patients with a previous history of hypersensitivity to lithium or any of the excipients contained in the tablets.

4.4 Special Warnings and Precautions for Use

Pretreatment physical examination and laboratory testing are required prior to commencement of therapy, and should be repeated at frequent intervals. The patient should maintain a normal diet with adequate salt and fluid intake during therapy.

Brugada syndrome.

Use with caution in the following circumstances.

Hypercalcemia and hyperparathyroidism.

Use in surgery.

Special precautions.

Check the following before use.

Paediatric use.

Use in the elderly.

Effects on laboratory tests.

4.5 Interactions with Other Medicines and Other Forms of Interactions

Clinicians should be aware that lithium may interact with a variety of drugs. Caution should, therefore, be exercised when lithium is coadministered with any other medication.
Ziprasidone can interact with lithium to augment the prolongation of the QTc interval.
Concurrent diuretics or angiotensin converting enzyme (ACE) inhibitors (such as captopril and enalapril) may be associated with changes in lithium clearance and should only be instituted with caution following reduction in lithium dosage and with subsequent monitoring of serum lithium levels (see Section 4.3 Contraindications). Thiazides show a paradoxical antidiuretic effect resulting in possible water retention and lithium intoxication. Similar precautions should be exercised on withdrawal of these agents.
Drugs which affect electrolyte balance such as steroids and appetite suppressants may alter lithium excretion. Drugs containing ionic sodium, e.g. sodium bicarbonate, may prevent the establishment or maintenance of adequate serum lithium levels.
Side effects of psychotropic drugs, such as neuroleptics (particularly haloperidol at higher doses), may be potentiated by lithium therapy. Consequently, concomitant dosage of these drugs should be reduced.
Lithium may prolong the effects of neuromuscular blocking agents.
Isolated cases have been reported of clinically significant interactions between lithium and calcium channel blockers, carbamazepine, diazepam, phenytoin, methyldopa, theophylline and fluoxetine (therefore, concomitant use of other SSRIs should be undertaken with caution as this combination may precipitate serotonin syndrome).
Calcium channel blockers may increase the neurotoxic effects of lithium, and serum lithium concentrations may need to be at the lower end of the therapeutic range.
Acetazolamide, urea, xanthine preparations and alkalinising agents, such as sodium bicarbonate, may lower serum lithium concentrations by increasing urinary lithium excretion.
Possible interactions may occur with imipramine and metronidazole.
Nonsteroidal anti-inflammatory drugs may cause an increase in serum lithium levels. This interaction is reported to be most marked with the more potent prostaglandin synthetase inhibitors, such as indomethacin and piroxicam. There is also evidence that other nonsteroidal anti-inflammatory agents, including the selective cyclooxygenase-2 (COX-2) inhibitors, have the same effect.
Lithium levels should be monitored very carefully when NSAIDs are first co-administered or discontinued.
Angiotensin II receptor antagonists (e.g. Atacand and Cozaar) can increase serum lithium concentrations when administered concurrently.
Patients should be encouraged to inform their doctor if signs of intoxication, such as polyuria, polydipsia or episodes of nausea and vomiting, occur.
Acute renal failure has been reported rarely with lithium toxicity.
SGLT2 inhibitors may increase renal lithium excretion and the blood lithium levels may be decreased. Serum concentration of lithium should be monitored more frequently after initiation and dose changes of SGLT2 inhibitors.

4.6 Fertility, Pregnancy and Lactation

(Category D)
Lithium enters the fetal circulation and cases of disturbance of the thyroid function of the newborn infant have been reported. Available data also indicate that lithium during pregnancy may cause malformations of the cardiovascular system.
Therefore, the potential benefits of continued administration during pregnancy must be weighed against the possible adverse effects. If administration of lithium is considered essential and continued during pregnancy, serum lithium levels must be monitored closely at routine intervals, particularly at parturition. Babies showing signs of lithium intoxication may require fluid therapy and they may have a flaccid appearance which returns to normal without treatment. It is strongly recommended that lithium be discontinued before a planned pregnancy.
Bottle feeding of infants is recommended as lithium is excreted in breast milk.

Effects on fertility.

4.7 Effects on Ability to Drive and Use Machines

Impaired driving performance or machine operation skills may occur in patients receiving lithium. At the beginning of treatment the occasional onset of fatigue can impair reflexes. Lithium may cause disturbances of the central nervous system (e.g. somnolence, dizziness, and hallucinations).

4.8 Adverse Effects (Undesirable Effects)

The occurrence and severity of adverse reactions are generally directly related to serum lithium concentrations as well as to individual sensitivity to lithium and generally occur more frequently and with greater severity at higher concentrations. The most frequent adverse effects are the initial postabsorptive symptoms, believed to be associated with a rapid rise in serum lithium levels. They include gastrointestinal discomfort with mild nausea and diarrhoea, vertigo, muscle weakness and a dazed feeling, and frequently disappear after stabilisation of therapy.
The more common and persistent adverse reactions are fine tremor of the hands, fatigue, thirst and polyuria. These do not necessarily require reduction of dosage. Nausea is usually transient.
Adverse effects occurring at therapeutic serum lithium concentrations include anorexia, constipation or diarrhoea, epigastric discomfort, metallic taste, headache, vertigo, fine tremor, polyuria with polydipsia, oedema, hypermagnesaemia and hypercalcaemia. Reversible ECG changes, e.g. T wave flattening or inversion, cardiac arrhythmias and EEG changes have been reported. Exacerbation of skin conditions (such as acne and psoriasis) and leucocytosis are relatively common side effects of lithium therapy. Significant weight gain is also observed in many patients receiving lithium.
Long-term administration of lithium carbonate may precipitate goitre requiring treatment with thyroxine, but this regresses when treatment is discontinued. Hair thinning and mild cognitive impairment may occur. Rarely, hyperthyroidism, hyperparathyroidism and nephrogenic diabetes insipidus have been reported.
Toxic effects may be expected at serum lithium concentrations over 1.5 mmol/L, although they can appear at lower concentrations. They call for immediate withdrawal of treatment and should always be considered very seriously. Signs of toxicity include increasing diarrhoea, vomiting, anorexia, severe abdominal discomfort, polyuria, muscle weakness, lethargy, ataxia, lack of coordination, tinnitus, blurred vision, dry mouth, dysgeusia and impotence/ sexual dysfunction, coarse tremor (marked) of the extremities and lower jaw, muscle hyperirritability and twitching, agitation, hyper-reflexia, choreoathetoid movements, dysarthria, disorientation, psychosis, drowsiness, seizures and coma. At higher concentrations, ataxia, tinnitus, blurred vision, giddiness and increasing polyuria are seen.
The following reactions appear to be related to serum lithium concentrations. Adverse reactions can occur in patients with serum concentrations within the therapeutic range (i.e. below 1.5 mmol/L or lower in the elderly).

Body as a whole.

Cardiovascular.

Dermatological.

Endocrine.

Gastrointestinal.

Haematological.

Hypersensitivity.

Neuromuscular/ CNS.

Renal.

Reporting suspected adverse events.

4.9 Overdose

Symptoms.

Treatment.

5 Pharmacological Properties

5.1 Pharmacodynamic Properties

Mechanism of action.

Clinical trials.

5.2 Pharmacokinetic Properties

No data available.

5.3 Preclinical Safety Data

Genotoxicity.

Carcinogenicity.

6 Pharmaceutical Particulars

6.1 List of Excipients

The tablets contain the inactive ingredients: dextrin, hypromellose, lactose monohydrate, macrogol 6000, magnesium stearate, sodium lauryl sulfate, sodium starch glycollate A, maize starch and talc-purified.

6.2 Incompatibilities

Incompatibilities were either not assessed or not identified as part of the registration of this medicine.

6.3 Shelf Life

2 years.

6.4 Special Precautions for Storage

Store below 30 degrees Celsius.

6.5 Nature and Contents of Container

White HDPE bottles with polypropylene child resistant caps.
200, *100 and *1000 tablets.
*Not currently marketed.

6.6 Special Precautions for Disposal

In Australia, any unused medicine or waste material should be disposed of by taking to your local pharmacy.

6.7 Physicochemical Properties

Molecular formula of lithium carbonate is Li₂O₃. It has a molecular weight of 73.9.

CAS number.

7 Medicine Schedule (Poisons Standard)

S4.

Summary Table of Changes